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Coordinated and sequential transcription of the cyprinid herpesvirus-3 annotated genes
Cyprinid herpesvirus-3 (CyHV-3) is the cause of a fatal disease in carp and koi fish. The disease is seasonal and appears when water temperatures range from 18 to 28°C. CyHV-3 is a member of the Alloherpesviridae, a family in the Herpesvirales order that encompasses mammalian, avian and reptilian viruses.
Arnon Dishon
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Susceptibility of cyprinid cultured cells to cyprinid herpesvirus 3
Archives of Virology, 2007Cyprinid herpesvirus 3 is a highly contagious and lethal virus that affects ornamental koi and common carp worldwide. However, it is not yet known whether other cyprinids are infected and/or harbor the virus. Here, we report that cultured cells derived from common carp, koi, silver carp and goldfish allow CyHV-3 propagation, while cyprinid cells ...
M, Davidovich +3 more
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Inhibiting cyprinid herpesvirus-3 replication with CRISPR/Cas9
Biotechnology Letters, 2015The potential of CRISPR/Cas9 gene editing to repress CyHV-3 was tested in vitro.By targeting two basic target genes necessary for the early transcription of CyHV-3, we show that virus transcription and particle release were significantly decreased by CRISPR/Cas9, as measured by quantitative real-time PCR and virus titration experiments, respectively.(A)
Yicheng, Zhao +6 more
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Intra vitam assays for detecting fish infected with cyprinid herpesvirus 3 (CyHV-3)
Diseases of Aquatic Organisms, 2022Koi carp is one of the most sensitive variants of common carp Cyprinus carpio to cyprinid herpesvirus 3, commonly known as koi herpesvirus (KHV). Given that this species is traded at high prices throughout the world, intra vitam assays for detecting KHV in targeted fish with a high detection efficiency are essential. In this study, 4 intra vitam assays
Kei, Yuasa +5 more
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Impact of cyprinid herpesvirus 3 (Koi herpesvirus) on wild and cultured fish.
CABI Reviews, 2016Abstract Common carp is a widespread freshwater fish inhabiting lower and mid streams of rivers and shallow confined waters in Eurasia. Carp aquaculture in shallow, man-made ponds has a long history and now common carp is the most widely cultured freshwater fish species in the world.
D. Steinhagen +2 more
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Molecular characterization of Cyprinid herpesvirus 3 encoded viral interleukin10
Fish & Shellfish Immunology, 2019Cyprinid herpesvirus 3 (CyHV-3), a virus that encodes an interleukin10 (IL-10) homologue, causes severe economic losses to the common carp and koi culture industry. The present study was devoted to this IL-10 homologue. Recombinant viral IL-10 (vIL-10) protein encoded by CyHV-3 ORF134 gene using prokaryotic expression system was obtained successfully ...
Ping Ouyang +13 more
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Pathogenesis of acute and chronic diseases caused by cyprinid herpesvirus‐3
Journal of Fish Diseases, 2014AbstractThe pathogenesis of cyprinid herpesvirus‐3 (CyHV‐3) was studied using different lineages of carp/koi. After exposure to the virus, infected cells were first found in the skin by histopathology and by in situ hybridization. The epidermis of the skin was most severely damaged and often sloughed off in the fish sampled on days 5 through 8, and the
S, Miwa +4 more
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Nationwide Cyprinid herpesvirus 3 contamination in natural rivers of Japan
Research in Veterinary Science, 2012Cyprinid herpesvirus 3 (CyHV-3) disease is a significant threat for common and koi carp cultivators and for freshwater ecosystems. To determine the prevalence of CyHV-3 in Japanese rivers, a nationwide survey of all national class-A rivers was undertaken in the Summer of 2008.
Toshifumi, Minamoto +4 more
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Biology and host response to Cyprinid herpesvirus 3 infection in common carp
Developmental & Comparative Immunology, 2014Viruses from the family Alloherpesviridae form an aquatic clade of herpesviruses infecting fish and amphibia. Diseases caused by these herpesviruses are of increasing importance because of the high morbidity and mortality associated with the infection, and the difficulties in diagnosing latently infected carriers.
Mikołaj, Adamek +5 more
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[Research Advances in Cyprinid Herpesvirus 3].
Bing du xue bao = Chinese journal of virology, 2016Cyprinid herpesvirus 3 (CyHV-3) is the causative agent of an extremely contagious and aggressive disease afflicting common corp Cyprinus carpio L. termed koi herpesvirus disease (KHVD). Since it was first reported in 1997, the virus has spread worldwide rapidly, leading to enormous financial losses in industries based on common carp and koi carp.
Shucheng, Zheng +7 more
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