Results 1 to 10 of about 1,866 (175)

CRISPR-Enhanced RAA-SHERLOCK Assay for Point-of-Care Detection of Cyprinid Herpesvirus-3: Development, Validation and Clinical Application. [PDF]

J Fish Dis
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Soliman H, Akram N, Saleh M.
europepmc   +2 more sources

Protective and Therapeutic Capacities of Lactic Acid Bacteria Postmetabolites against Koi Herpesvirus Infection In Vitro [PDF]

Life, 2023
Background: The accumulation of data on beneficial biological effects of probiotics and their metabolic products favors their potential use in the prevention and treatment of various malaises. Methods: Nine postmetabolites from Lactic acid bacteria (LAB)
Neli Vilhelmova-Ilieva, Svetla Danova, Zdravka Petrova, Lili Dobreva, Georgi Atanasov, Kapka Mancheva, Lora Simeonova   +6 more
doaj   +2 more sources

Protective effects of immersion immunization of koi with Escherichia coli DH5α carrying DNA vaccine against koi herpesvirus [PDF]

Fish and Shellfish Immunology Reports, 2023
This study aims to immunize the koi fingerlings immersion using the formalin-killed and freeze-dried E. coli DH5α carrying plasmid for the KHV DNA vaccine. 200 fish on each tank in a total water volume of 20 L.
Jauharotul Afifah, Sukenda Sukenda, Alimuddin Alimuddin, Hasan Nasrullah, Sri Nuryati   +4 more
doaj   +2 more sources

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans. [PDF]

Clin Pharmacol Ther
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Chen S, Chen H, Xu S.
europepmc   +2 more sources

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]

Aquac Nutr
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc   +2 more sources

Transcriptomic Responses to Koi Herpesvirus in Isolated Blood Leukocytes from Infected Common Carp [PDF]

Viruses
Koi herpesvirus (KHV, CyHV-3) causes severe economic losses in carp farms. Its eradication is challenging due to the establishment of latency in blood leukocytes and other tissues.
Irene Cano, Ellen Blaker, David Hartnell, Audrey Farbos, Karen A. Moore, Adele Cobb, Eduarda M. Santos, Ronny van Aerle   +7 more
doaj   +2 more sources

Rapid, non-invasive, visual point-of-care detection of koi herpesvirus using loop-mediated isothermal amplification [PDF]

Frontiers in Immunology
IntroductionKoi herpesvirus (KHV or CyHV-3) causes a highly contagious and lethal disease in common carp and koi, resulting in substantial economic losses in global aquaculture. Rapid point-of-care testing (POCT) of KHV is critical for curbing its spread
Na Jiang, Na Jiang, Jianlin Luo, Chuiyu Kong, Zhihong Ma, Lin Luo, Xingchen Huo, Yan Chen, Huanhuan Yu, Jian Gao, Jinjing Zhang, Jinjing Zhang, Jinyou Hu, Dongjie Shi, Dongjie Shi   +14 more
doaj   +2 more sources

Development of an attenuated vaccine against Koi Herpesvirus Disease (KHVD) suitable for oral administration and immersion [PDF]

npj Vaccines, 2022
Since the end of the1990ies, Cyprinid herpesvirus 3 (also known as koi herpesvirus, KHV) has caused mass mortality events of koi and common carp all over the globe. This induced a high economic impact, since the KHV disease cannot be cured up to now, but
Sandro Klafack, Lars Schröder, Yeonhwa Jin, Matthias Lenk, Pei-Yu Lee, Walter Fuchs, Jean-Christophe Avarre, Sven M. Bergmann   +7 more
doaj   +2 more sources

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Koi herpes virus disease (KHV)

EFSA Journal, 2017
Koi herpes virus (KHV) disease has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of KHV disease to be listed, Article 9 for the ...
Antonio Velarde, Margaret Good, Andrew Butterworth   +2 more
exaly   +2 more sources

EXPRESSION OF HSP70 IN KOI HERPESVIRUS-INFECTED TILAPIA (OREOCHROMIS NILOTICUS) [PDF]

Russian Journal of Agricultural and Socio-Economic Sciences, 2019
Koi herpesvirus (KHV) not only can infect cyprinidae, but also infect other freshwater fishes. It causes KHV to spread widely throughout the world. Infection of KHV in fish has several symptoms and one of them is increased HSP70 expression.
Wahidi B.R., Yanuhar U., Fadjar M., Andayani S.   +3 more
doaj   +1 more source