Investigation of Cyprinid Herpesvirus 3 (CyHV-3) Disease Periods and Factors Influencing CyHV-3 Transmission in A Low Stocking Density Infection Trial [PDF]
Animals, 2021 Cyprinid herpesvirus 3 (CyHV-3) is the etiological agent of koi herpesvirus disease (KHVD) and important pathogen of aquaculture and wild populations of common carp worldwide.
Isaiah E. Tolo +4 more
doaj +6 more sources
Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs. [PDF]
PLoS ONE, 2015 MicroRNAs (miRNAs) are a class of small non-coding RNAs involved in post-transcriptional gene regulation. Some viruses encode their own miRNAs and these are increasingly being recognized as important modulators of viral and host gene expression. Cyprinid
Owen H Donohoe +5 more
doaj +10 more sources
Host microRNA analysis in cyprinid Herpesvirus-3 (CyHV-3) infected common carp [PDF]
BMC Genomics, 2019 Background The mechanism of latency and the ability of the cyprinid herpesvirus 3 (CyHV-3) to establish life-long infections in carp remains poorly understood.
Michal Reichert +6 more
doaj +6 more sources
Integrative Transcriptomic Analysis Reveals the Immune Mechanism for a CyHV-3-Resistant Common Carp Strain [PDF]
Frontiers in Immunology, 2021 Anti-disease breeding is becoming the most promising solution to cyprinid herpesvirus-3 (CyHV-3) infection, the major threat to common carp aquaculture.
Zhiying Jia, Mijuan Shi, Xiao-Qin Xia
exaly +8 more sources
Cloning and Identification of Common Carp (Cyprinus carpio) PI3KC3 and Its Expression in Response to CyHV-3 Infection [PDF]
Current Issues in Molecular BiologyPhosphoinositide 3-kinases (PI3Ks) are a class of key regulatory factors in eukaryotes that can inhibit viral replication by influencing autophagy. Currently, cyprinid herpesvirus 3 (CyHV-3) poses a serious threat to common carp culture.
Xiaona Jiang +8 more
doaj +5 more sources
Anti-CyHV-3 effect of fluorescent, tricyclic derivative of acyclovir 6-(4-MeOPh)-TACV in vitro [PDF]
Journal of Veterinary Research, 2019 Cyprinid herpesvirus 3 (CyHV-3) is a virus infecting carp with disease symptoms of gill necrosis, fish discoloration, sunken eyes, and mortality reaching 90%.
Troszok Agnieszka +5 more
doaj +4 more sources
Targeted genomic enrichment and sequencing of CyHV-3 from carp tissues confirms low nucleotide diversity and mixed genotype infections [PDF]
PeerJ, 2016 Koi herpesvirus disease (KHVD) is an emerging disease that causes mass mortality in koi and common carp, Cyprinus carpio L. Its causative agent is Cyprinid herpesvirus 3 (CyHV-3), also known as koi herpesvirus (KHV).
Saliha Hammoumi +6 more
doaj +5 more sources
CRISPR-Enhanced RAA-SHERLOCK Assay for Point-of-Care Detection of Cyprinid Herpesvirus-3: Development, Validation and Clinical Application. [PDF]
J Fish DisABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Soliman H, Akram N, Saleh M.
europepmc +2 more sources
Investigation of β-Carboline Alkaloid Harmaline Against Cyvirus cyprinidallo3 Infection In Vitro and In Vivo [PDF]
VirusesCyvirus cyprinidallo3, also known as Cyprinid herpesvirus 3 (CyHV-3), is a common pathogen of koi and common carp (Cyprinus carpio). Infection of CyHV-3 can lead to high mortality in fry under 4 months of age.
Clement Manes +5 more
doaj +2 more sources
The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]
Aquac NutrViral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc +2 more sources