Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs.
PLoS ONE, 2015 MicroRNAs (miRNAs) are a class of small non-coding RNAs involved in post-transcriptional gene regulation. Some viruses encode their own miRNAs and these are increasingly being recognized as important modulators of viral and host gene expression. Cyprinid
Owen H Donohoe +5 more
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Skin mucus of
Veterinary Research, 2011 Cyprinid herpesvirus 3 (CyHV-3) is the aetiological agent of a mortal and highly contagious disease in common and koi carp. The skin is the major portal of entry of CyHV-3 in carp after immersion in water containing the virus.
Raj Victor +14 more
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Integrative Transcriptomic Analysis Reveals the Immune Mechanism for a CyHV-3-Resistant Common Carp Strain [PDF]
Frontiers in Immunology, 2021 Anti-disease breeding is becoming the most promising solution to cyprinid herpesvirus-3 (CyHV-3) infection, the major threat to common carp aquaculture.
Zhiying Jia +28 more
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Host microRNA analysis in cyprinid Herpesvirus-3 (CyHV-3) infected common carp [PDF]
BMC Genomics, 2019 Background The mechanism of latency and the ability of the cyprinid herpesvirus 3 (CyHV-3) to establish life-long infections in carp remains poorly understood.
Michal Reichert +6 more
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Anti-CyHV-3 effect of fluorescent, tricyclic derivative of acyclovir 6-(4-MeOPh)-TACV in vitro
Journal of Veterinary Research, 2019 Cyprinid herpesvirus 3 (CyHV-3) is a virus infecting carp with disease symptoms of gill necrosis, fish discoloration, sunken eyes, and mortality reaching 90%.
Troszok Agnieszka +5 more
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Veterinární Medicína, 2018 Cyprinid herpesvirus 3 (CyHV-3), also known as koi herpesvirus, is the causative agent of the highly contagious koi herpesvirus disease, which is restricted to koi and common carp and causes significant losses in both fish stock.
A. Pospichal +3 more
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Modulation of Sodium and Ammonia Transporters in the Context of Viral Gill Diseases in Common Carp (Cyprinus carpio) [PDF]
Journal of Fish Diseases, Volume 48, Issue 10, October 2025.ABSTRACT Osmoregulation and ammonia removal are among key physiological processes that take place in gills and affect fish homeostasis and well‐being. These processes can be disrupted by numerous environmental factors, but also by viral infections, especially those leading to severe gill disorders.
Maria Zawisza +5 more
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Current Issues in Molecular BiologyPhosphoinositide 3-kinases (PI3Ks) are a class of key regulatory factors in eukaryotes that can inhibit viral replication by influencing autophagy. Currently, cyprinid herpesvirus 3 (CyHV-3) poses a serious threat to common carp culture.
Xiaona Jiang +8 more
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Rational development of an attenuated recombinant cyprinid herpesvirus 3 vaccine using prokaryotic mutagenesis and in vivo bioluminescent imaging. [PDF]
PLoS Pathogens, 2015 Cyprinid herpesvirus 3 (CyHV 3) is causing severe economic losses worldwide in common and koi carp industries, and a safe and efficacious attenuated vaccine compatible with mass vaccination is needed.
Maxime Boutier +13 more
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Different transcriptional response between susceptible and resistant common carp (Cyprinus carpio) fish hints on the mechanism of CyHV-3 disease resistance [PDF]
BMC Genomics, 2019 Background Infectious disease outbreaks form major setbacks to aquaculture production and to further development of this important sector. Cyprinid herpes virus-3 (CyHV-3) is a dsDNA virus widely hampering production of common carp (Cyprinus carpio), one
Roni Tadmor-Levi +7 more
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