Results 141 to 150 of about 34,415 (185)

Hyperhomocysteinemia in premature arterial disease: examination of cystathionine β-synthase alleles at the molecular level [PDF]

, 2017
Hyperhomocysteinemia occurs in approximately 30% of the patients with premature occlusive arterial disease (POAD). Some of these exhibit significantly reduced fibroblast cystathionine β-synthase (CBS) activities, suggesting that they may be heterozygous ...
Boers, Godfried H.J., de Franchis, Raffaella, Fowler, Brian, Graham, Ian, Kozich, Viktor, Kraus, Eva, Kraus, Jan P.   +6 more
core  

Examination of two different proteasome inhibitors in reactivating mutant human cystathionine β-synthase in mice. [PDF]

PLoS One, 2023
Gupta S, Lee HO, Wang L, Kruger WD.
europepmc   +1 more source

Role of Sex and Early Life Stress Experience on Porcine Cardiac and Brain Tissue Expression of the Oxytocin and H₂S Systems

Biomolecules
Early life stress (ELS) significantly increases the risk of chronic cardiovascular diseases and may cause neuroinflammation. This post hoc study, based on the material available from a previous study showing elevated “serum brain injury markers” in male ...
Franziska Münz, Nadja Abele, Fabian Zink, Eva-Maria Wolfschmitt, Melanie Hogg, Claus Barck, Josef Anetzberger, Andrea Hoffmann, Michael Gröger, Enrico Calzia, Christiane Waller, Peter Radermacher, Tamara Merz   +12 more
doaj   +1 more source

Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

Communications Biology
There are limited therapeutic options for patients with advanced prostate cancer (PCa). We previously found that heat shock factor 1 (HSF1) expression is increased in PCa and is an actionable target.
J. Spencer Hauck, David Moon, Xue Jiang, Mu-En Wang, Yue Zhao, Lingfan Xu, Holly Quang, William Butler, Ming Chen, Everardo Macias, Xia Gao, Yiping He, Jiaoti Huang   +12 more
doaj   +1 more source

Homocysteine plasma levels in patients treated with antiepileptic drugs depend on folate and vitamin B12 serum levels, but not on genetic variants of homocysteine metabolism [PDF]

, 2017
Background: Antiepileptic drugs (AEDs) are commonly used in the treatment of epilepsy, psychiatric diseases and pain disorders. Several of these drugs influence blood levels of folate and vitamin B12 and, consequently, homocysteine.
Elger, Christian, Linnebank, Michael, Moskau-Hartmann, Susanna, Semmler, Alexander, Stoffel-Wagner, Birgit   +4 more
core  

A Methionine-Portioning-Based Medical Nutrition Therapy with Relaxed Fruit and Vegetable Consumption in Patients with Pyridoxine-Nonresponsive Cystathionine-β-Synthase Deficiency. [PDF]

Nutrients, 2023
Uygur E, Aktuglu-Zeybek C, Aghalarov M, Cansever MS, Kıykım E, Zubarioglu T.   +5 more
europepmc   +1 more source

Relationships Between H₂S and OT/OTR Systems in Preeclampsia

Antioxidants
Pre-eclampsia (PE) is a hypertensive pregnancy complication. Oxidative stress is hypothesized to contribute to the pathophysiology of PE. Both the hydrogen sulfide (H2S) and oxytocin (OT) systems might play a role in the pathophysiology of PE, like their
Tamara Merz, Sarah Ecker, Nicole Denoix, Oscar McCook, Stefanie Kranz, Ulrich Wachter, Edit Rottler, Thomas Papadopoulos, Christoph Fusch, Cosima Brucker, Jakob Triebel, Thomas Bertsch, Peter Radermacher, Christiane Waller   +13 more
doaj   +1 more source

Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

Proceedings of the National Academy of Sciences of the United States of America, 2013
C. Szabó, C. Coletta, C. Chao, Katalin Módis, B. Szczesny, A. Papapetropoulos, M. Hellmich   +6 more
semanticscholar   +1 more source

Helicobacter pylori infection and serum homocysteine in hemodialysis patient [PDF]

, 2012
Hyperhomocysteinemia is a factor that is found to be responsible for the development of atherosclerosis in the setting of chronic Helicobacter pylori (H. Pylori) infection.
Baradaran, Azar., Ghobadi, Shamin., Maghsoudi, Ahmad Reza., Nasri, Hamid., Rafieian-Kopaei, Mahmoud.   +4 more
core  

The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-β-synthase domain. [PDF]

FEBS J, 2022
Knejzlík Z, Doležal M, Herkommerová K, Clarova K, Klíma M, Dedola M, Zborníková E, Rejman D, Pichová I.   +8 more
europepmc   +1 more source