Results 121 to 130 of about 1,104,559 (168)

Effect of long-term chronic hyperhomocysteinemia on retinal structure and function in the cystathionine-β-synthase mutant mouse. [PDF]

Exp Eye Res, 2022
Xiao H, Wang J, Barwick SR, Yoon Y, Smith SB.   +4 more
europepmc   +1 more source

Loss of cystathionine-β-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. [PDF]

Biochem Pharmacol
Thibodeau J, Zhao J, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Hershberger K, Su Y, Arroum T, Pham L, Pavelich L, Awdish R, LaValley J, Boucher AC, Chen W, Li J, Bao X, Hüttemann M, Back JB, Allen JE, Prabhu VV, Crispino JD, Taub JW, Ge Y.   +24 more
europepmc   +1 more source

Homocystinuria and hyperhomocysteinaemia in the Western Cape

, 2002
Thesis (DTech (Biomedical Technology)) -- Cape Technikon, 2002Research into the role of homocyst(e)ine in cellular functions was stimulated by homocystinuria, a severe autosomal recessive disorder caused by, in the classic case, deficiency of ...
Human, Lucille
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Abnormal Trophoblast Invasion in Early-Onset Preeclampsia: The Involvement of Cystathionine β-Synthase, Specificity Protein 1 and microRNA-22. [PDF]

Cureus
Arora P, Kalra S, Dhingra R, Kshetrapal P, Bhatla N, Dwivedi S.   +5 more
europepmc   +1 more source

Enhancing virtual screening of cystathionine β-synthase inhibitors: benchmarking target-specific machine-learning scoring functions against state-of-the-art AI docking and co-folding approaches. [PDF]

J Cheminform
Truong CM, To VT, Janel N, Dairou J, Ballester PJ, Taboureau O, Tran-Nguyen VK.   +6 more
europepmc   +1 more source

H₂S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins. [PDF]

Biomedicines, 2023
Islam RK, Donnelly E, Donnarumma E, Hossain F, Gardner JD, Islam KN.   +5 more
europepmc   +1 more source

Down-Regulated Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase in Varicocele, and Infertile Men: A Case-Control Study. [PDF]

Cell J, 2022
Akbarian F, Tavalaee M, Dattilio M, Nasr-Esfahani MH.   +3 more
europepmc   +1 more source

Brain-Derived Cystathionine β-Synthase-Generated H₂S Attenuates Cerebral Ischemia-Reperfusion Injury via VEGFR₂-Mediated Angiogenesis in MCAO/R Rats. [PDF]

Curr Issues Mol Biol
Liang S, Jiang, Jiang Y, Wang S, Jiang JR, Wen JY, Chen ZW, Chen S.   +7 more
europepmc   +1 more source

Cystathionine β-synthase overexpression drives metastatic dissemination in pancreatic ductal adenocarcinoma via inducing epithelial-to-mesenchymal transformation of cancer cells. [PDF]

Redox Biol, 2022
Czikora Á, Erdélyi K, Ditrói T, Szántó N, Jurányi EP, Szanyi S, Tóvári J, Strausz T, Nagy P.   +8 more
europepmc   +1 more source

Structural insights into mutations of cystathionine beta-synthase

, 2003
Cystathionine beta-synthase (CBS) is a unique heme-containing enzyme that catalyses a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of
Kraus, J. P., Oliveriusova, J., Burkhard, P., Meier, M.   +3 more
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