Results 111 to 120 of about 1,104,559 (168)

Dual targeting of H₂S synthesizing enzymes; cystathionine β-synthase and cystathionine γ-lyase by miR-939-5p effectively curbs triple negative breast cancer. [PDF]

Heliyon, 2023
Nafea H, Youness RA, Dawoud A, Khater N, Manie T, Abdel-Kader R, Bourquin C, Szabo C, Gad MZ.   +8 more
europepmc   +1 more source

Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells. [PDF]

Antioxidants (Basel), 2023
Santos SS, Rodrigues LOCP, Martins V, Petrosino M, Zuhra K, Ascenção K, Anand A, Abdel-Kader RM, Gad MZ, Bourquin C, Szabo C.   +10 more
europepmc   +1 more source

Homocystinuria: studies on cystathionine beta-synthase, S-adenosylmethionine synthetase and cystathionase activities in skin fibroblasts

, 1981
Cystathionine beta-synthase, S-adenosylmethionine synthetase and cystathionase activities were assayed in skin fibroblast cultures from five pyridoxine responsive and five pyridoxine non-responsive homocystinurics, six obligate heterozygotes for ...
Carson, N.A., Bittles, A.H.
core  

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria

Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 5'-phosphate (PLP)-dependent enzyme in the transsulfuration pathway, responsible for ...
Martínez-Cruz, Luis Alfonso, Nasrallah, Gheyath K, Al-Sadeq, Duaa W, Al-Dewik, Nader, Astegno, Alessandra, Conter, Carolina, Nasrallah, Gheyath K., Thanassoulas, Angelos, Nomikos, Michail, Al-Sadeq, Duaa W., Safieh-Garabedian, Bared   +10 more
core   +1 more source

The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-β-synthase domain. [PDF]

FEBS J, 2022
Knejzlík Z, Doležal M, Herkommerová K, Clarova K, Klíma M, Dedola M, Zborníková E, Rejman D, Pichová I.   +8 more
europepmc   +1 more source

How to fix a broken protein: restoring function to mutant human cystathionine β-synthase. [PDF]

Hum Genet, 2022
Kruger WD.
europepmc   +1 more source

Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. [PDF]

Elife, 2022
Zhu H, Chan KT, Huang X, Cerra C, Blake S, Trigos AS, Anderson D, Creek DJ, De Souza DP, Wang X, Fu C, Jana M, Sanij E, Pearson RB, Kang J.   +14 more
europepmc   +1 more source

Involvement of cystathionine β-synthase in ATP-induced hydrogen sulfide production in cochlear outer hair cells. [PDF]

J Otol
Harada N, Ito Y, Takashima I, Ojida A, Sekiguchi F, Kawabata A.   +5 more
europepmc   +1 more source

Role of the cystathionine β-synthase / H₂S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome. [PDF]

Redox Biol, 2022
Panagaki T, Pecze L, Randi EB, Nieminen AI, Szabo C.   +4 more
europepmc   +1 more source

Cystathionine β-synthase is inhibited by epinephrine and norepinephrine over-secretion via NF-κB activation in stress-induced hyperhomocysteinemia. [PDF]

Sci Rep
Zhang L, Wu S, Xie F, Wang X, Sun Z, Zhao Y, Qian L.   +6 more
europepmc   +1 more source