Results 101 to 110 of about 1,104,559 (168)

Biogenesis of Hydrogen Sulfide and Thioethers by Cystathionine Beta-Synthase

, 2019
Aims: The transsulfuration pathway enzymes cystathionine beta-synthase (CBS) and cystathionine gammalyaseare thought to be the major source of hydrogen sulfide (H2S).
Jakub Krijt (6422104), Jitka Sokolová (564065), Maria A Ralat (6440447), Jesse F. Gregory III (420118), Michaela Krizkova (6440446), Jana O. Kent (1898485), Jan P. Kraus (6422100), Viktor Kožich (6422106), Tomas Majtan (6422097)   +8 more
core   +1 more source

Examination of two different proteasome inhibitors in reactivating mutant human cystathionine β-synthase in mice. [PDF]

PLoS One, 2023
Gupta S, Lee HO, Wang L, Kruger WD.
europepmc   +1 more source

Homocysteine metabolism.

, 2013
Homocysteine is metabolized to methionine by remethylation and cystathionine by transsulfuration. Coenzymes are shown in gray. BHMT, betaine-homocysteine S-methyltransferase; DMG, dimethylglycine; MAT, methionine adenosyltransferase; SAM, S ...
Lina Wang (44695), Yi-Hsuan Pan (404765), Yijian Zhang (404766), Tengteng Zhu (501315), Shuyi Zhang (34553)   +4 more
core   +1 more source

Relationships Between H₂S and OT/OTR Systems in Preeclampsia

Antioxidants
Pre-eclampsia (PE) is a hypertensive pregnancy complication. Oxidative stress is hypothesized to contribute to the pathophysiology of PE. Both the hydrogen sulfide (H2S) and oxytocin (OT) systems might play a role in the pathophysiology of PE, like their
Tamara Merz, Sarah Ecker, Nicole Denoix, Oscar McCook, Stefanie Kranz, Ulrich Wachter, Edit Rottler, Thomas Papadopoulos, Christoph Fusch, Cosima Brucker, Jakob Triebel, Thomas Bertsch, Peter Radermacher, Christiane Waller   +13 more
doaj   +1 more source

Aerobic and anaerobic metabolism of cysteine. H₂S formed enzymatically from L- or D-cysteine, in mitochondria is transformed to sulfite which in the reaction catalyzed by SO is oxidized to sulfate (aerobic pathway). Anaerobic metabolism of L-cysteine leads via synthesis of H₂S and its further sulfhydration to the formation of sulfane sulfur compounds.

, 2016
Abbreviations: CBS—cystathionine β-synthase; CSE—γ-cystathionase; CDO—cysteine dioxygenase; SO—sulfite oxidase; TSR—thiosulfate reductase; TST—rhodanese.
Karolina Wydra (848377), Ewa Nowak (848378), Magdalena Górny (848379), Danuta Kowalczyk-Pachel (848375), Lidia Włodek (848381), Elżbieta Lorenc-Koci (848382), Małgorzata Iciek (848376), Małgorzata Filip (848380)   +7 more
core   +1 more source

Inhibition of fungal pathogenicity by targeting the H₂S-synthesizing enzyme cystathionine β-synthase. [PDF]

Sci Adv, 2022
Chang W, Zhang M, Jin X, Zhang H, Zheng H, Zheng S, Qiao Y, Yu H, Sun B, Hou X, Lou H.   +10 more
europepmc   +1 more source

Synthesis of Inhibitors of Cystathionine β-Synthase

, 2014
Hydrogen sulfide (H2S) is well known for its harmful effects to the environment, yet within the last decade evidence of its role as an endogenous gasotransmitter has surfaced. Both overproduction and underproduction of H2S can lead to detrimental health
Guajardo, Alyssa Michelle 1989-
core  

Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly. [PDF]

Cell Prolif, 2022
Cao Y, Zhu X, Zhen P, Tian Y, Ji D, Xue K, Yan W, Chai J, Liu H, Wang W.   +9 more
europepmc   +1 more source

Dataset for: Specific Down-regulation of Cystathionine β-synthase Expression in the Kidney during Obesity

, 2018
Hydrogen sulfide (H2S) is recognized as a novel gasotransmitter involved in the regulation of nervous system, cardiovascular functions, inflammatory response, gastrointestinal system and renal function.
Zhanjun Jia (4838784), Mokan Deng (4838799), Kexin Peng (4838790), Fei Wang (4838796), Tianxin Yang (4838793), Mi Liu (4838781), Jiahui Su (4838778), Yu Lin (4838787)   +7 more
core   +1 more source

A Methionine-Portioning-Based Medical Nutrition Therapy with Relaxed Fruit and Vegetable Consumption in Patients with Pyridoxine-Nonresponsive Cystathionine-β-Synthase Deficiency. [PDF]

Nutrients, 2023
Uygur E, Aktuglu-Zeybek C, Aghalarov M, Cansever MS, Kıykım E, Zubarioglu T.   +5 more
europepmc   +1 more source