Results 121 to 130 of about 10,826 (180)

3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells

Frontiers in Pharmacology, 2017
Hypoxia-induced angiogenesis is a common phenomenon in many physiological and patho-physiological processes. However, the potential differential roles of three hydrogen sulfide producing systems cystathionine γ-lyase (CSE)/H2S, cystathionine β-synthase ...
Beibei Tao, Rui Wang, Chen Sun, Yichun Zhu   +3 more
doaj   +1 more source

Cystathionine-γ-lyase promotes the metastasis of breast cancer via the VEGF signaling pathway

International Journal of Oncology, 2019
The present study aimed to provide data to support the association between cystathionine-γ-lyase (CSE) and breast cancer metastasis. Reverse transcription-quantitative polymerase chain reaction, immunohistochemistry and western blot analysis were used to
Lupeng Wang, HAI-MIN Shi, Ya Liu, Weiyuan Zhang, Xiaofan Duan, Ming Li, Xiaoyan Shi, Tianxiao Wang   +7 more
semanticscholar   +1 more source

Hydrogen Sulfide, a Toxic Gas with Cardiovascular Properties in Uremia: How Harmful Is It? [PDF]

, 2011
Hydrogen sulfide (H2S) is a poisonous gas which can be lethal. However, it is also produced endogenously, thus belonging to the family of gasotransmitters along with nitric oxide and carbon monoxide. H2S is in fact involved in mediating several signaling
Capasso, Rosanna, De Santo, Natale G., Ingrosso, Diego, Lanza, Diana, Perna, Alessandra F., Raiola, Ilaria, Sepe, Immacolata   +6 more
core   +1 more source

Hydrogen sulfide and its role in female reproduction

Frontiers in Veterinary Science
Hydrogen sulfide (H2S) is a gaseous signaling molecule produced in the body by three enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Aneta Pilsova, Zuzana Pilsova, Barbora Klusackova, Natalie Zelenkova, Eva Chmelikova, Pavla Postlerova, Marketa Sedmikova   +6 more
doaj   +1 more source

Significance of Hydrogen Sulfide Production in the Pancreatic β-Cell

Journal of Pharmacological Sciences, 2011
.: Hydrogen sulfide (H2S) is an important signaling molecule in various mammalian cells and tissues. H2S is synthesized from l-cysteine and regulates several cellular and physiological phenomena (vasorelaxation, hormone secretion, and apoptosis) and ...
Shigeki Taniguchi, Ichiro Niki
doaj   +1 more source

Identification of Proteins Interacting with Cytoplasmic High-Mobility Group Box 1 during the Hepatocellular Response to Ischemia Reperfusion Injury [PDF]

, 2017
Ischemia/reperfusion injury (IRI) occurs inevitably in liver transplantations and frequently during major resections, and can lead to liver dysfunction as well as systemic disorders.
Dahmen, Uta, Dirsch, Olaf, Fang, Haoshu, Kan, Chunyi, Kniemeyer, Olaf, Krüger, Thomas, Settmacher, Utz, Wei, Weiwei, Xie, Chichi, Zhang, Tianjiao   +9 more
core   +2 more sources

Allosteric activators of cystathionine γ lyase to augment endogenous hydrogen sulfide and inhibit pathologic calcification

Pharmacological Research
Hydrogen sulfide (H₂S), a gasotransmitter naturally produced in the body by enzymes such as cystathionine γ lyase (CSE), helps reduce inflammation, oxidative stress, and abnormal tissue calcification.
Sonia Nasi, Driss Ehirchiou, Cindy Blatter, Veronique Chobaz, Stefan Germann, Alexandra Brandenberger, Elias Bommeli, Emiko Uchikawa, Giuseppe Cirino, Rainer Riedl, Alexander So, Nathalie Busso   +11 more
doaj   +1 more source

내흉동맥과 요골동맥의 황화수소 합성효소의 발현 양상 비교 분석: 관상동맥우회도관으로서 미치는 영향 [PDF]

, 2022
학위논문(박사) -- 서울대학교대학원 : 의과대학 의학과, 2022. 8. 김웅한.Objectives: The molecular basis supporting the superiority of the left internal thoracic artery (LITA) as a bypass conduit is limited.
강윤진
core  

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

British Journal of Pharmacology, 2013
Hydrogen sulfide (H2S) is a signalling molecule that belongs to the gasotransmitter family. Two major sources for endogenous enzymatic production of H2S are cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). In the present study, we examined
Antonia Asimakopoulou, Panagiotis Panopoulos, Christos T. Chasapis, C. Coletta, Zongmin Zhou, G. Cirino, A. Giannis, C. Szabó, G. Spyroulias, A. Papapetropoulos   +9 more
semanticscholar   +1 more source

Hydrogen sulphide synthesis (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]

, 2019
Hydrogen sulfide is a gasotransmitter, with similarities to nitric oxide and carbon monoxide. Although the enzymes indicated below have multiple enzymatic activities, the focus here is the generation of hydrogen sulphide (H2S) and the enzymatic ...
Billiar, Timothy R., Cirino, Giuseppe, Fulton, David, Motterlini, Roberto, Papapetropoulos, Andreas, Szabo, Csaba   +5 more
core   +2 more sources