Results 51 to 60 of about 36,977 (144)

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages. [PDF]

, 2016
Published onlineJOURNAL ARTICLEAIMS: Macrophages are of key importance for tissue repair after myocardial infarction (MI). Hydrogen sulfide (H2S) has been shown to exert cardioprotective effects in MI.
Miao, L, Moore, PK, Shen, X, Shen, Y, Whiteman, M, Xin, H, Xin, X, Zhu, Y   +7 more
core   +1 more source

Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.

Cancer Research, 2017
The trans-sulfuration enzyme cystathionine-β-synthase (CBS) and its product hydrogen sulfide (H2S) are aberrantly upregulated in colorectal cancers, where they contribute to tumor growth and progression by both autocrine and paracrine mechanisms. However,
Ches'Nique M. Phillips, J. Zatarain, M. E. Nicholls, Craig Porter, S. Widen, K. Thanki, Paul Johnson, M. Jawad, M. Moyer, James W Randall, Judy L. Hellmich, Manjit Maskey, S. Qiu, T. Wood, N. Druzhyna, B. Szczesny, Katalin Módis, C. Szabó, C. Chao, M. Hellmich   +19 more
semanticscholar   +1 more source

Genome-Wide Investigation and Expression Profiling Under Abiotic Stresses of a Soybean Unknown Function (DUF21) and Cystathionine-β-Synthase (CBS) Domain-Containing Protein Family

Biochemical Genetics, 2020
Cystathionine-β-synthase (CBS) domain-containing proteins (CDCPs) constitute a large family in plants, and members of this family have been implicated in a variety of biological processes.
Qingnan Hao, Yanyan Yang, Z. Shan, Haifeng Chen, Chanjuan Zhang, Limiao Chen, Songli Yuan, Xiaojuan Zhang, Shuilian Chen, Zhong-lu Yang, Dezhen Qiu, Xinan Zhou   +11 more
semanticscholar   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Purification and Characterization of Cystathionine γ-Synthase from Thermoacidophilic Archaea Sulfolobus tokodaii [PDF]

, 2010
The gene encoding a cystathionine γ-synthase from Sulfolobus tokodaii was cloned and expressed in Escherihia coli Rosetta-gami (DE3). Cystathionine γ-synthase ［EC 2. 5. 1.
Endou, Yuuichi, Inagaki, Kenji, Kaneda, Shouichirou, Kudou, Daizou, Kuramitsu, Seiki, Shinozaki, Mai, Tamura, Takashi, Yanagitani, Masahiko   +7 more
core  

A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery [PDF]

, 2017
Hypoxia-induced coronary artery vasodilatation protects the heart by increasing blood flow under ischemic conditions, however its mechanism is not fully elucidated.
Alexander, Stephen P.H., Donovan, J., Dunn, William R., Garle, M.J., Ralevic, Vera, Roberts, Richard E., Wong, P.S.   +6 more
core   +2 more sources

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Transcriptome dynamics in the asexual cycle of the chordate Botryllus schlosseri [PDF]

, 2016
Background: We performed an analysis of the transcriptome during the blastogenesis of the chordate Botryllus schlosseri, focusing in particular on genes involved in cell death by apoptosis. The tunicate B.
Ballarin, Loriano, Ballin, Francesca, Campagna, Davide, Franchi, Nicola, Gasparini, Fabio, Manni, Lucia, Valle, Giorgio, Vitulo, Nicola   +7 more
core   +3 more sources

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system. [PDF]

, 2017
There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two ...
Bucci, M., Cirino, G, Vellecco, V
core   +1 more source