Results 61 to 70 of about 1,025,233 (163)
Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction
Scientific Reports, 2022 Persulfidation contributes to a group of redox post-translational modifications (PTMs), which arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) action.
Hedvika Řimnáčová +11 more
doaj +1 more source
AMPK‐Mediated Lipid Metabolic Reprogramming in Cancer: From Mechanisms to Targeted Therapies
Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.ABSTRACT AMP‐activated protein kinase (AMPK), a key regulator of cellular energy metabolism, is activated under conditions of energy stress to restore metabolic homeostasis by promoting catabolic pathways and inhibiting anabolic processes such as lipid synthesis. Multiple key molecules involved in lipid metabolism are regulated by AMPK, and its role in
Yuying Chen, Wen Liu, Bing Luo
wiley +1 more source
Normal taurine synthesis in cystathionine beta-synthase knockout mice.
, 2004 Normal taurine synthesis in cystathionine beta-synthase knockout ...
Wei-Hsun. Chao (7982912)
core +6 more sources
Health Care Science, Volume 5, Issue 5, Page 495-513, October 2026.This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying +6 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.Polyphenols target oxidative stress and inflammation, improving endothelial function and reducing blood pressure in systemic arterial hypertension. Created by BioRender.com. ABSTRACT Systemic arterial hypertension (SAH) remains a leading global cause of premature death, significantly increasing the risk of cardiovascular, cerebrovascular, and renal ...
Agnes Ciafrino +7 more
wiley +1 more source
, 2016 Human cystathionine β-synthase is one of two key enzymes involved in intracellular metabolism of homocysteine. It catalyzes a β-replacement reaction in which the thiolate of homocysteine replaces the hydroxyl group of serine to give the product ...
Jungwon Hwang (2945127) +4 more
core +1 more source
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT Ferroptosis is a form of programmed cell death characterized by iron‐dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this process.
Xiaoqian Tang +5 more
wiley +1 more source
Production of hydrogen sulfide from D-cysteine and its therapeutic potential
Frontiers in Endocrinology, 2013 Accumulating evidence shows that H2S has physiological functions in various tissues and organs. It includes regulation of neuronal activity, vascular tension, a release of insulin, and protection of the heart, kidney and brain from ischemic insult. H2S
Norihiro eShibuya, Hideo eKimura
doaj +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
Food Frontiers, Volume 7, Issue 5, September 2026.The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Homocystinuria presenting as a calcified right atrial mass
Annals of Pediatric Cardiology, 2018 Homocystinuria is a genetic inborn error of metabolism due to the deficiency of cystathionine β-synthase resulting in increased serum homocysteine and methionine and decreased cysteine which predisposes affected individuals to arterial and venous ...
Tahleel Altaf Shera +3 more
doaj +1 more source