Results 51 to 60 of about 1,025,233 (163)
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Smart Molecules, EarlyView.Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
, 2010 The catalytic potential for H 2 S biogenesis and homocysteine clearance converge at the active site of cystathionine β-synthase (CBS), a pyridoxal phosphate-dependent enzyme.
Janet L. Smith +3 more
core +1 more source
L-cysteine/cystathionine-β-synthase-induced relaxation in mouse aorta involves a L-serine/sphingosine-1-phosphate/NO pathway [PDF]
, 2020 Among the three enzymes involved in the transsulfuration pathway, only cystathionine β-synthase (CBS) converts L-cysteine into L-serine and H2 S. L-serine is also involved in the de novo sphingolipid biosynthesis through a condensation with palmitoyl-CoA
d'Emmanuele di Villa Bianca R. +6 more
core +1 more source
British Journal of Pharmacology, EarlyView.Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo +4 more
wiley +1 more source
, 2018 Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug ...
Bartosz Szczesny (16538) +25 more
core +1 more source
Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants
Plant, Cell &Environment, EarlyView.ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain ...
Mervin Chun‐Yi Ang +13 more
wiley +1 more source
Crystal structure of cystathionine β-synthase from honeybee Apis mellifera
, 2019 Cystathionine β-synthase (CBS), the key enzyme in the transsulfuration pathway, links methionine metabolismto the biosynthesis of cellular redox controlling molecules.
Juraj Majtán (427560) +7 more
core +1 more source
Cross‐species transcriptomics uncovers shared responses to water deficiency in plants
The Plant Genome, Volume 19, Issue 4, December 2026.Abstract Deepening our knowledge of conserved molecular mechanisms governing stress responses in plants is fundamental for identifying new core genes and processes involved in tolerance to adverse environmental conditions. For this purpose, we developed a bioinformatic pipeline to retrieve and integrate stress‐related RNA‐seq transcriptomic data from ...
Francesco Punzi +5 more
wiley +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk +39 more
wiley +1 more source
Antioxidants, 2022 It is now well established that the urothelium does not act as a passive barrier but contributes to bladder homeostasis by releasing several signaling molecules in response to physiological and chemical stimuli.
Emma Mitidieri +12 more
doaj +1 more source