Results 11 to 20 of about 5,592 (129)

Global Survey, Expressions and Association Analysis of CBLL Genes in Peanut

Frontiers in Genetics, 2022
Cystathionine γ-synthase (CGS), methionine γ-lyase (MGL), cystathionine β-lyase (CBL) and cystathionine γ-lyase (CGL) share the Cys_Met_Meta_PP domain and play important roles in plant stress response and development.
Weifang Ren, Weifang Ren, Weifang Ren, Zhaocong Zeng, Zhaocong Zeng, Zhaocong Zeng, Sijian Wang, Sijian Wang, Sijian Wang, Juncheng Zhang, Jiahai Fang, Jiahai Fang, Jiahai Fang, Liyun Wan, Liyun Wan, Liyun Wan   +15 more
doaj   +1 more source

Dietary restriction transforms the mammalian protein persulfidome in a tissue-specific and cystathionine γ-lyase-dependent manner

Nature Communications, 2021
Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent ...
Nazmin Bithi, Christopher Link, Yoko O. Henderson, Suzie Kim, Jie Yang, Ling Li, Rui Wang, Belinda Willard, Christopher Hine   +8 more
doaj   +1 more source

Harnessing the Benefits of Endogenous Hydrogen Sulfide to Reduce Cardiovascular Disease

Antioxidants, 2021
Cardiovascular disease is the leading cause of death in the U.S. While various studies have shown the beneficial impact of exogenous hydrogen sulfide (H2S)-releasing drugs, few have demonstrated the influence of endogenous H2S production.
Kevin M. Casin, John W. Calvert
doaj   +1 more source

Mutant Huntingtin Derails Cysteine Metabolism in Huntington’s Disease at Both Transcriptional and Post-Translational Levels

Antioxidants, 2022
Cysteine is a semi-essential amino acid that not only plays an essential role as a component of protein synthesis, but also in the generation of numerous sulfur-containing molecules such as the antioxidant glutathione and coenzyme A. We previously showed
Bindu D. Paul, Juan I. Sbodio, Solomon H. Snyder   +2 more
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Mechanism-based and computational modeling of hydrogen sulfide biogenesis inhibition: interfacial inhibition

Scientific Reports, 2023
Hydrogen sulfide (H2S) is a gaseous signaling molecule that participates in various signaling functions in health and diseases. The tetrameric cystathionine γ-lyase (CSE) contributes to H2S biogenesis and several investigations provide evidence on the ...
Laurent Le Corre, Dominique Padovani
doaj   +1 more source

Influence of sex hormones on DNA content and cystathionine-γ-lyase expression in rat myocardium

Zaporožskij Medicinskij Žurnal, 2017
Till now sexual features of cystathionine-γ-lyase/H2S system functioning in heart and its relationship to DNA content in myocardial cells nuclei depending on the level of sex hormones.
A. V. Melnik , N. V. Zaichko, I. L. Chereshnyuk, О. А. Khodakіvskyi, O. А. Haiduk   +4 more
doaj   +1 more source

Endogenous H2S producing enzymes are involved in apoptosis induction in clear cell renal cell carcinoma

BMC Cancer, 2018
Background Knowledge about the expression and thus a role of enzymes that produce endogenous H2S - cystathionine-β-synthase, cystathionine γ-lyase and mercaptopyruvate sulfurtransferase - in renal tumors is still controversial.
Jan Breza, Andrea Soltysova, Sona Hudecova, Adela Penesova, Ivan Szadvari, Petr Babula, Barbora Chovancova, Lubomira Lencesova, Ondrej Pos, Jan Breza, Karol Ondrias, Olga Krizanova   +11 more
doaj   +1 more source

Enhanced expression of cystathionine β-synthase and cystathionine γ-lyase during acute cholecystitis-induced gallbladder inflammation. [PDF]

PLoS ONE, 2013
BACKGROUND: Hydrogen sulfide (H2S) has recently been shown to play an important role in the digestive system, but the role of endogenous H2S produced locally in the gallbladder is unknown.
Li Zhang, Chenwei Pan, Bin Yang, Yong Xiao, Baoping Yu   +4 more
doaj   +1 more source

Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.

PLoS Pathogens, 2021
Hydrogen sulfide (H2S) has recently been recognized as a novel gaseous transmitter with several anti-inflammatory properties. The role of host- derived H2S in infections by Pseudomonas aeruginosa was investigated in clinical and mouse models.
Georgios Renieris, Dionysia-Eirini Droggiti, Konstantina Katrini, Panagiotis Koufargyris, Theologia Gkavogianni, Eleni Karakike, Nikolaos Antonakos, Georgia Damoraki, Athanasios Karageorgos, Labros Sabracos, Antonia Katsouda, Elisa Jentho, Sebastian Weis, Rui Wang, Michael Bauer, Csaba Szabo, Kalliopi Platoni, Vasilios Kouloulias, Andreas Papapetropoulos, Evangelos J Giamarellos-Bourboulis   +19 more
doaj   +1 more source

Endogenous Hydrogen Sulfide Contributes to Tone Generation in Porcine Lower Esophageal Sphincter Via Na+/Ca2+ Exchanger

Cellular and Molecular Gastroenterology and Hepatology, 2018
Hydrogen sulfide (H2S) is a major physiologic gastrotransmitter. Its role in the regulation of the lower esophageal sphincter (LES) function remains unknown. The present study addresses this question.
Xiaopeng Bai, Eikichi Ihara, Katsuya Hirano, Yoshimasa Tanaka, Kayoko Nakano, Satomi Kita, Takahiro Iwamoto, Haruei Ogino, Mayumi Hirano, Yoshinao Oda, Kazuhiko Nakamura, Yoshihiro Ogawa   +11 more
doaj   +1 more source