Results 71 to 80 of about 5,592 (129)

Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure. [PDF]

Redox Rep, 2023
Wu D, Sun Y, Gu Y, Zhu D.
europepmc   +1 more source

Dissecting molecular mechanisms underlying ferroptosis in human umbilical cord mesenchymal stem cells: Role of cystathionine γ-lyase/hydrogen sulfide pathway. [PDF]

World J Stem Cells, 2023
Hu B, Zhang XX, Zhang T, Yu WC.
europepmc   +1 more source

[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function. [PDF]

Oncol Rep
Chen L, Li X, Liu L, Yu B, Xue Y, Liu Y.
europepmc   +1 more source

<i>Helicobacter pylori</i>-induced cystathionine-γ-lyase drives redox imbalance and metabolic remodeling in gastric cancer. [PDF]

J Gastrointest Oncol
Wang Y, Xu R, Wang Z, Wu Y, Han S, Zhang X, Li H.   +6 more
europepmc   +1 more source

Cystathionine γ-Lyase-Dependent S-Sulfhydration of Smad3: A Novel Target to Alleviate Fibrosis in Systemic Sclerosis. [PDF]

Arthritis Rheumatol
Liu J, Xiao Y, Liu L, Xiao X, Pi Z, Song Z, Yang Q, Zeng Z, Zhu R, Shi Y, Xiao R.   +10 more
europepmc   +1 more source

Multiomic screening of invasive GBM cells reveals targetable transsulfuration pathway alterations

The Journal of Clinical Investigation
While the poor prognosis of glioblastoma arises from the invasion of a subset of tumor cells, little is known of the metabolic alterations within these cells that fuel invasion.
Joseph H. Garcia, Erin A. Akins, Saket Jain, Kayla J. Wolf, Jason Zhang, Nikita Choudhary, Meeki Lad, Poojan Shukla, Jennifer Rios, Kyounghee Seo, Sabraj A. Gill, William H. Carson, Luis R. Carette, Allison C. Zheng, David R. Raleigh, Sanjay Kumar, Manish K. Aghi   +16 more
doaj   +1 more source

Reactive Sulfur Species Produced by Cystathionine γ-lyase Function in the Establishment of Mesorhizobium loti-Lotus japonicus Symbiosis. [PDF]

Microbes Environ, 2023
Fukudome M, Ishizaki H, Shimokawa Y, Mori T, Uchi-Fukudome N, Umnajkitikorn K, Murakami EI, Uchiumi T, Kawaguchi M.   +8 more
europepmc   +1 more source

The Association Between Hyperketonemia and Reduced Circulating Hydrogen Sulfide in Children with Type 1 Diabetes, and Ketone Inhibition of Cystathionine-γ-Lyase mRNA Expression in Cultured Hepatocytes. [PDF]

Genes (Basel)
Jain SK, Parsanathan R, Justin Margret J, Gungor N, Vanchiere JA, Mhanna MJ, McVie R.   +6 more
europepmc   +1 more source

Chromobox 3 assembles an epigenetic complex contributing to cystathionine γ-lyase-mediated protection against aortic aneurysm/dissection. [PDF]

Nat Commun
Zhao Y, Cui C, Gao H, Yao Y, Niu Y, Cheng L, Shao X, Zhang H, Wang Y, Lin Y, Dong Z, Wu H, Chen Z, Yang L, Geng B.   +14 more
europepmc   +1 more source

Dual targeting of H₂S synthesizing enzymes; cystathionine β-synthase and cystathionine γ-lyase by miR-939-5p effectively curbs triple negative breast cancer. [PDF]

Heliyon, 2023
Nafea H, Youness RA, Dawoud A, Khater N, Manie T, Abdel-Kader R, Bourquin C, Szabo C, Gad MZ.   +8 more
europepmc   +1 more source