Results 71 to 80 of about 12,769 (186)

Dissociation of Alzheimer's morphological pathology from cognitive impairment [PDF]

, 2009
We observed the Alzheimer's morphological pathology, amyloid production induces Alzheimer's cognitive impairment, was dissociated from the cognitive impairment.
Nobuyuki Mikoda, Tohru Hasegawa
core   +1 more source

Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]

, 2015
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz, CONTESTABILE, Maria Teresa, FAMELI, VALERIA, Mollo, Roberto, Perdicchi, Andrea, RECUPERO, Santi Maria   +5 more
core   +3 more sources

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. [PDF]

, 2016
Ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine) is a trimethylated and sulphurised histidine derivative which exhibits antioxidant properties. Here we report that deletion of Aspergillus fumigatus egtA (AFUA_2G15650), which encodes a trimodular
A Braunshausen, A Palumbo, A Vit, A Vit, A Wallner, B Halliwell, C Burns, C Collins, C Davis, D Gründemann, DH Scharf, DJ Steenkamp, F Lessing, FP Seebeck, G Pontecorvo, G Rieder, GL Russo, GT Mashabela, GW Jones, H Haas, H Haas, H Oberegger, HS Spies, I Mouyna, J Aguirre, J Carlsson, J Cox, J Ey, KA O’Hanlon, KJ Sheridan, KV Goncharenko, L Gallagher, L Muszkieta, L Servillo, M Deiana, M Eisendle, M Schrettl, M Schrettl, M Schrettl, M Schrettl, M Thon, MH Bello, MH Bello, ML Nielsen, MR Ariyanayagam, NG Markova, OI Aruoma, PK Chang, RA Owens, RC Fahey, RN Vogt, S Carberry, S Paris, S Ravanel, S Sotgia, S Sotgia, SK Dolan, SS Spicer, T Hartmann, T Kubodera, T Pluskal, T Song, TP Holler, W Fang, Ö Sarikaya-Bayram   +64 more
core   +1 more source

Hydrogen Sulfide: Redox Metabolism and Signaling [PDF]

, 2011
The recognition of hydrogen sulfide (H2S) as an endogenously produced gas with signaling potential has stimulated research on a multitude of physiological effects mediated in the cardiovascular, immune, gastrointestinal, genitourinary, endocrine, and ...
Banerjee, Ruma
core   +1 more source

Sulfur metabolism actively promotes initiation of cell division in yeast. [PDF]

PLoS ONE, 2009
BACKGROUND:Sulfur metabolism is required for initiation of cell division, but whether or not it can actively promote cell division remains unknown. METHODOLOGY/PRINCIPAL FINDINGS:Here we show that yeast cells with more mtDNA have an expanded reductive ...
Heidi M Blank, Shefali Gajjar, Andrey Belyanin, Michael Polymenis   +3 more
doaj   +1 more source

Cystathionine Beta Synthase as a Risk Factor for Alzheimer Disease

Current Alzheimer Research, 2004
One of the known risk factors for developing Alzheimer disease (AD) is hyperhomocysteinemia. The latter may result from mutations of the genes coding for three key enzymes involved in homocysteine metabolism (methylenetetrahydrofolate reductase [MTHFR], methionine synthase [MS], and cystathionine beta-synthase [CBS]).
Beyer, K, Lao, JI, Carrato, C, Rodriguez-Vila, A, Latorre, P, Mataro, M, Llopis, MA, Mate, JL, Ariza, A   +8 more
openaire   +5 more sources

Engineering of methionine-auxotroph Escherichia coli via parallel evolution of two enzymes from Corynebacterium glutamicum's direct-sulfurylation pathway enables its recovery in minimal medium

Metabolic Engineering Communications
Methionine biosynthesis relies on the sequential catalysis of multiple enzymes. Escherichia coli, the main bacteria used in research and industry for protein production and engineering, utilizes the three-step trans-sulfurylation pathway catalyzed by L ...
Matan Gabay, Inbar Stern, Nadya Gruzdev, Adi Cohen, Lucia Adriana-Lifshits, Tamar Ansbacher, Itamar Yadid, Maayan Gal   +7 more
doaj   +1 more source

Arylthioamides and aryliminothioethers as new slow H2S-releasing agents [PDF]

Hydrogen sulphide (H2S) is emerging as an important endogenous modulator, which exhibits the beneficial effects of nitric oxide (NO) on the cardiovascular (CV) system, without producing toxic metabolites.
ANGELINI, MARIAGRAZIA
core  

Isolated aortic root dilation in homocystinuria [PDF]

, 2017
BACKGROUND: Vascular complications in homocystinuria have been known for many years, but there have been no reports to date on involvement of the ascending aorta.
Davison, JE, Elliott, PM, Guha, N, Kemp, H, Lachmann, R, Lorenzini, M, Murphy, E, Pandya, B, Pitcher, A   +8 more
core   +2 more sources

Protective effect of hydrogen sulfide on oxidative stress-induced neurodegenerative diseases

Neural Regeneration Research, 2020
Hydrogen sulfide is an antioxidant molecule that has a wide range of biological effects against oxidative stress. Balanced oxidative stress is also vital for maintaining cellular function in biological system, where reactive oxygen species are the main ...
Rubaiya Tabassum, Na Young Jeong, Junyang Jung   +2 more
doaj   +1 more source