Results 71 to 80 of about 4,040 (150)

Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis

Frontiers in Immunology, 2018
Chronic inflammation contributes to tumor initiation in colitis-associated colorectal cancer (CRC). Indeed, inflammatory bowel disease (IBD) patients show an increased risk of developing CRC.
Paola De Cicco, Theodore Sanders, Giuseppe Cirino, Kevin J. Maloy, Angela Ianaro   +4 more
doaj   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

An atlas of plant selenium metabolism

New Phytologist, Volume 250, Issue 4, Page 2041-2060, May 2026.
Summary Selenium (Se) is not only a rare and toxic element but also an essential micronutrient for humans and animals that is often in short supply. Terrestrial plants do not require Se, but it can have growth‐promoting or negative effects, depending on the exposure level.
Jeroen van der Woude, Mark G. M. Aarts, Michela Schiavon, Antony van der Ent   +3 more
wiley   +1 more source

Immunoresponsive Gene 1–Itaconate Exacerbates Hypertension by Inhibiting the Cystathionine Gamma-Lyase/Hydrogen Sulfide Pathway

Journal of Cardiovascular Development and Disease
The role of immunoresponsive gene 1 (IRG1)–itaconate (ITA) in hypertension remains poorly understood. This study aimed to investigate this role and the underlying mechanisms.
Minglu Ma, Chenyu Fan, Shuping Han, Hu Wang, Yuzhou Xue, Boyang Lv, He Huang, Hongfang Jin, Ling Jin, Jian Liu   +9 more
doaj   +1 more source

Enhancing Postharvest Quality of Fresh-Cut Changgen Mushrooms by Exogenous L-Cysteine Treatment: Aspects of Accumulating Amino Acids, Triggering Energy Metabolism and Enhancing Endogenous H₂S Regulation

Foods
As a rare and functional edible mushroom, the market potential of ready-to-eat fresh-cut Changgen mushrooms (Oudemansiella raphanipes) is booming in developing countries.
Xingchi Ma, Tianhao Li, Weijian Mao, Yu Zhang, Haoran Liu, Wenwen Jiang, Yanan Sun, Hao Yu, Fansheng Cheng, Dan Zhu   +9 more
doaj   +1 more source

Effect of cysteine on the inactivation of cystathionine gamma-lyase by D,L-propargylglycine.

Acta medica Okayama, 1989
In vivo inactivation of cystathionine gamma-lyase by D,L-propargylglycine, a suicide inhibitor, was found to be less profound in rat kidney than in the liver. We investigated the cause of this difference using rat tissues. We fractionated kidney extract to characterize the substance which protected enzyme, and found that cysteine exhibits protecting ...
Awata, Shiro, Nakayama, Kazuko, Suzuki, Isao, Kodama, Hiroyuki   +3 more
openaire   +3 more sources

Identification of probasin-related antigen as cystathionine gamma-lyase by molecular cloning.

Journal of Biological Chemistry, 1994
We reported previously that a monoclonal antibody against probasin (rat prostatic secretory protein) recognizes a 40-kDa protein localized in rat liver and kidney. The protein (probasin-related antigen, PRB-RA) may participate in a specific differentiated function of these tissues.
N, Nishi, H, Tanabe, H, Oya, M, Urushihara, H, Miyanaka, F, Wada   +5 more
openaire   +2 more sources

Calcium Sensing Receptor Regulating Smooth Muscle Cells Proliferation Through Initiating Cystathionine-Gamma-Lyase/Hydrogen Sulfide Pathway in Diabetic Rat

Cellular Physiology and Biochemistry, 2015
Aims: Hydrogen sulfide (H2S) inhibits the proliferation of vascular smooth muscle cells (VSMCs). However, how cystathionine-gamma-lyase (CSE), a major enzyme that produces H2S, is regulated remains unknown.
Xin Zhong, Yuwen Wang, Jichao Wu, Aili Sun, Fan Yang, Dan Zheng, Ting Li, Shiyun Dong, Yajun Zhao, Guangdong Yang, Changqing Xu, Dianjun Sun, Fanghao Lu, Weihua Zhang   +13 more
doaj   +1 more source

Allosteric activators of cystathionine γ lyase to augment endogenous hydrogen sulfide and inhibit pathologic calcification

Pharmacological Research
Hydrogen sulfide (H₂S), a gasotransmitter naturally produced in the body by enzymes such as cystathionine γ lyase (CSE), helps reduce inflammation, oxidative stress, and abnormal tissue calcification.
Sonia Nasi, Driss Ehirchiou, Cindy Blatter, Veronique Chobaz, Stefan Germann, Alexandra Brandenberger, Elias Bommeli, Emiko Uchikawa, Giuseppe Cirino, Rainer Riedl, Alexander So, Nathalie Busso   +11 more
doaj   +1 more source

Hydrogen sulfide and its role in female reproduction

Frontiers in Veterinary Science
Hydrogen sulfide (H2S) is a gaseous signaling molecule produced in the body by three enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Aneta Pilsova, Zuzana Pilsova, Barbora Klusackova, Natalie Zelenkova, Eva Chmelikova, Pavla Postlerova, Marketa Sedmikova   +6 more
doaj   +1 more source