Results 51 to 60 of about 555,922 (178)

Cystathionine .GAMMA.-lyase activity in the cephamycin C producer Streptomyces lactamdurans.

The Journal of Antibiotics, 1981
Extracts of the cephamycin C producer S. lactamdurans were found to possess cystathionine gamma-lyase activity (E.C. 4.4.1.1). This represents the first demonstration of this enzyme of the reverse transsulfuration pathway in a prokaryotic organism. A likely involvement of reverse transsulfuration in antibiotic synthesis is indicated by the fact that ...
B A, Kern, E, Inamine
openaire   +3 more sources

Volatile Sulfur Compounds as a Predictor for Esophagogastroduodenal Mucosal Injury

Gut and Liver, 2008
Background/Aims: Halitosis is a symptom that bothers patients more socially than medically and its pathogenic mechanisms are unclear and treatment armamenterium is limited. Clinicians generally ignored active interventions.
doaj   +1 more source

Two-photon ratiometric imaging of endogenous reactive inorganic sulfur species in the cellular cushion toward formaldehyde

Biosensors and Bioelectronics: X, 2023
To address the potential biological relationship between reactive inorganic sulfur species (RISSs) and formaldehyde, the novel two-photon ratiometric RISSs probes (PH-RISSs) were synthesized practically with high selectivity and sensitivity toward RISSs ...
Linye Wu, Bo Wang, Gangqin Xi, Yajuan Fu, Shuting Yu, Qi Chen, Jianxin Chen, Liqin Zheng, Shuangmu Zhuo, Daliang Li   +9 more
doaj   +1 more source

Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study.

, 2009
The generation of endogenous hydrogen sulphide may either limit or contribute to the degree of tissue injury caused by ischaemia/reperfusion injury.
Rocha J, Tripatara, P., Sepodes, B., Renshaw, Derek, Mota-Filipe, Helder, Tripatara P, Brancaleone, V., Thiemermann, C., Perretti, Mauro, Rocha, J., Perretti, M., BRANCALEONE, VINCENZO, Thiemermann, Christoph, Perretti M, Thiemermann C., Renshaw, D., Patel, Nimesh S A, Rocha, Joao, Patel, Nimesh S. A., Sepodes, Bruno, Mota-Filipe, H., Renshaw, Derek; id_orcid, Mota Filipe H, Patel NS, Sepodes B, Patel, N.S.A., Tripatara, Pinpat, Renshaw D   +27 more
core   +1 more source

Colorimetric coupled enzyme assay for cystathionine β-synthase [PDF]

, 2016
A colorimetric coupled enzyme assay for the determination of cystathionine β-synthase activity is described. The method exploits cystathionine γ-lyase as an ancillary enzyme capable of transforming cystathionine, produced by cystathionine β-synthase ...
BALESTRI, FRANCESCO, MOSCHINI, ROBERTA, MURA, UMBERTO, Rocchiccioli, Marco, DEL CORSO, ANTONELLA, Cappiello, Laura, CAPPIELLO, MARIO   +6 more
core   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

Advanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang, Liyue Wang, Xuan Wang, Xinran Li, Hao Xing, Lu Sun, Zhen Xi, Long Yi   +7 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Cysteine Persulfide Formation by Enterobacteriaceae Bacteria and Cloned Mammalian Cystathionine γ-Lyase [PDF]

, 2021
Polysulfides and persulfides (RSSxR and RSSH) have become topics of significant interest due to prevalence in eukaryotic and prokaryotic systems. Cysteine trisulfide (CysSSSCys) has been found to be able to be reduced by Escherichia coli and produce ...
Irwin, Drew
core