Cystathionine gamma lyase and hydrogen sulfide: new players in orthodontic root resorption. [PDF]
Ann Transl Med, 2020 Holliday LS, Dolce C.
europepmc +3 more sources
Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying Mechanisms. [PDF]
Antioxid Redox Signal, 2016 Aims: To investigate the regulation of hepatic glucose production by cystathionine γ-lyase (CSE)-generated hydrogen sulfide (H 2 S) in hepatic glucose production under physiological conditions.
Untereiner AA, Wang R, Ju Y, Wu L.
europepmc +4 more sources
Endogenous Hydrogen Sulfide Is an Important Factor in Maintaining Arterial Oxygen Saturation
Frontiers in Pharmacology, 2021 The gasotransmitter H2S is involved in various physiological and pathophysiological processes. The aim of this study was to investigate the physiological functions of H2S in the lungs.
Yan Huang +11 more
doaj +1 more source
Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis [PDF]
International Journal of Molecular Sciences, 2019 Madhav Bhatia +2 more
exaly +2 more sources
The Role of Hydrogen Sulfide in Plaque Stability
Antioxidants, 2022 Atherosclerosis is the greatest contributor to cardiovascular events and is involved in the majority of deaths worldwide. Plaque rapture or erosion precipitates life-threatening thrombi, resulting in the obstruction blood flow to the heart (acute ...
Qian Lin, Bin Geng
doaj +1 more source
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells [PDF]
Cardiovascular Research, 2010 Cystathionine gamma-lyase (CSE)-derived H2S plays an important role in regulating cell growth. Lack of CSE expression results in development of hypertension. The current study compared proliferation of smooth muscle cells derived from CSE gene knockout mice (SMCs-KO) with that of wild-type mice (SMCs-WT).Cell proliferation was assessed by ...
Guangdong, Yang +5 more
openaire +2 more sources
Overexpression of Cystathionine gamma-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3 [PDF]
, 2015 Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) disorder caused by a CAG repeat expansion in the ataxin-3 (ATXN3) gene resulting in toxic protein aggregation. Inflammation and oxidative stress are considered secondary factors contributing
Mitrović, Aleksandra D. +26 more
core +3 more sources
The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]
, 2009 Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Patel Pushpa +23 more
core +1 more source
The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts. [PDF]
Oncotarget, 2017 Hydrogen sulfide (H2S), generated in the osteoblasts predominantly via cystathionine-γ-lyase (CSE), is bone protective. Previous studies suggested that the onset of bone loss due to estrogen deficiency is associated to decreased levels of H2S and blunted gene expression of CSE. However, there are still a lot of unknowns on how H2S levels influence bone
Lambertini E +8 more
europepmc +4 more sources
Scientific Reports, 2021 Ginseng (Panax ginseng Meyer) is commonly used as an herbal remedy worldwide. Few studies have explored the possible physiological changes in the liver although patients often self-medicate with ginseng preparations, which may lead to exceeding the ...
Ann-Yae Na +8 more
doaj +1 more source