Results 1 to 10 of about 43,347 (262)
Cystatin C and uncontrolled hypertension [PDF]
The Anatolian Journal of Cardiology, 2020 Objective: Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study ...
Oğuz Karaca +7 more
core +6 more sources
Cystatin C and Cardiovascular Risk [PDF]
Clinical Chemistry, 2009 Patients with chronic kidney disease (CKD) are at high risk for developing cardiovascular disease (CVD) and cardiovascular events. Cystatin C, a protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum ...
J. C. Kaski, W. Koenig, TAGLIERI, NEVIO
core +7 more sources
Comparative analysis of cystatin superfamily in platyhelminths. [PDF]
PLoS ONE, 2015 The cystatin superfamily is comprised of cysteine proteinase inhibitors and encompasses at least 3 subfamilies: stefins, cystatins and kininogens. In this study, the platyhelminth cystatin superfamily was identified and grouped into stefin and cystatin ...
Aijiang Guo
doaj +2 more sources
Antioxidants, 2021 Stefin B (cystatin B) is an inhibitor of endo-lysosomal cysteine cathepsin, and the loss-of-function mutations in the stefin B gene were reported in patients with Unverricht–Lundborg disease (EPM1), a form of progressive myoclonus epilepsy.
Mojca Trstenjak Prebanda +3 more
doaj +1 more source
eJHaem, 2023 Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D‐dimers are also commonly elevated despite systemic hypofibrinolysis.
Kevin H. Toomer +6 more
doaj +1 more source
Journal of Health Care for the Poor and Underserved, 2010 Cystatins, the classical inhibitors of C1 cysteine proteinases, have been extensively studied and reviewed in the literature. Over the last 20 years, however, proteins containing cystatin domains but lacking protease inhibitory activities have been identified, and most likely more will be described in the near future.
Josiah, Ochieng, Gautam, Chaudhuri
openaire +2 more sources
Kidney Medicine, 2023 Rationale & Objective: Use of cystatin C in addition to creatinine to estimate glomerular filtration rate (estimated glomerular filtration rate based on cystatin C [eGFRcys] and estimated glomerular filtration rate based on creatinine [eGFRcr ...
Yeli Wang +14 more
doaj +1 more source
The Role of Exosomes in the Pathophysiology of Chronic Rhinosinusitis
Frontiers in Cellular and Infection Microbiology, 2022 Non-invasive biomarker analysis has made repetitive and painless sampling over time possible. Exosomes are being released from a parent cell and their cargo mirrors the cell micromilieu of the parent cell. Therefore, exosomes are promising surrogates for
Sarina K. Mueller
doaj +1 more source
Frontiers in Immunology, 2021 Despite the enormous morbidity attributed to schistosomiasis, there is still no vaccine to combat the disease for the hundreds of millions of infected people.
Mark S. Pearson +14 more
doaj +1 more source
Therapeutic Effect of Schistosoma japonicum Cystatin on Atherosclerotic Renal Damage
Frontiers in Cell and Developmental Biology, 2021 Atherosclerosis is a chronic inflammation of the arterial vessel wall driven by lipid metabolism disorders. Although helminthic infection and their derivatives have been identified to attenuate the chronic inflammatory diseases, the immunomodulatory ...
Huijuan Yang +22 more
doaj +1 more source