Results 11 to 20 of about 64,052 (260)
Journal of Health Care for the Poor and Underserved, 2010 Cystatins, the classical inhibitors of C1 cysteine proteinases, have been extensively studied and reviewed in the literature. Over the last 20 years, however, proteins containing cystatin domains but lacking protease inhibitory activities have been identified, and most likely more will be described in the near future.
Josiah, Ochieng, Gautam, Chaudhuri
openaire +2 more sources
Pharmaceuticals, 2020 Clan C1A or ‘papain superfamily’ cysteine proteases are key players in many important physiological processes and diseases in most living systems. Novel approaches towards the development of their inhibitors can open new avenues in translational medicine.
Manasi Mishra +4 more
doaj +1 more source
Hepatology, EarlyView., 2022 Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino +14 more
wiley +1 more source
Frontiers in Microbiology, 2022 IntroductionThe industrial yeast Pichia pastoris is widely used as a cell factory to produce proteins, chemicals and advanced biofuels. We have previously constructed P. pastoris strains that overexpress protein disulfide isomerase (PDI), which is a kind
Tingting Niu +9 more
doaj +1 more source
Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages
Cells, 2019 Stefin B (cystatin B) is an intracellular inhibitor of cysteine cathepsins and mutations in the stefin B gene, resulting in the development of Unverricht−Lundborg disease, which is a form of myoclonic epilepsy. It was suggested that a key mechanism
Mojca Trstenjak Prebanda +3 more
doaj +1 more source
Biotechnology & Biotechnological Equipment, 2023 Cystatin plays a crucial role in immune evasion by parasites. It regulates diverse immune response processes, such as antigen presentation, cytokine and NO production, and phagocytosis.
Lin Huang +3 more
doaj +1 more source
Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. [PDF]
, 2013 Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Kirwan, CJ, Macphee, IA, Philips, BJ
core +2 more sources
Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]
, 2007 OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek +5 more
core +1 more source
Expression of a barley cystatin gene in maize enhances resistance against phytophagous mites by altering their cysteine-proteases [PDF]
, 2011 Phytocystatins are inhibitors of cysteine-proteases from plants putatively involved in plant defence based on their capability of inhibit heterologous enzymes.
A Kiggundu +49 more
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Кардиоваскулярная терапия и профилактика, 2012 Aim. To assess the prognostic performance of the GRACE scale extended by cystatin C levels in the prediction of ischemic and hemorrhagic in-hospital complications among patients with acute coronary syndrome (ACS). Material and methods.
M. S. Kharchenko +4 more
doaj +1 more source