Results 141 to 150 of about 60,453 (247)

Association of HDL‐C Levels with Stroke and All‐cause Mortality: A Prospective Cohort Study from the CHARLS

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
In Chinese people over 45 years old, HDL‐C was a protective factor for stroke, while it had no significant association with all‐cause mortality. ABSTRACT Background Stroke has always been a huge medical challenge faced by China. Previous studies have found a negative correlation between high‐density lipoprotein cholesterol (HDL‐C) and stroke, but in ...
Zhi Liu, Libo Liang, Xiao Du, He He
wiley   +1 more source

Allergy to Cats: Current Perspectives and Therapeutic Options

open access: yesClinical and Translational Allergy, Volume 16, Issue 3, March 2026.
ABSTRACT Allergic rhinitis (AR) and asthma caused by cat dander have a highly variable prevalence across countries, which can reach 30% of the population in some regions. Cat allergens are widely distributed in the environment, making exposure nearly unavoidable, even in non‐cat‐owning households.
Pascal Demoly   +8 more
wiley   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

open access: yes
Experimental Physiology, EarlyView.
Anders Møller Greve   +4 more
wiley   +1 more source

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 669-677, March 2026.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing   +7 more
wiley   +1 more source

Biomarkers of Drug‐Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 608-617, March 2026.
This manuscript describes the scope of implementation and impact of a regulatory agency‐qualified panel of six urine biomarkers on drug development, the process for which was conducted and funded by the Critical Path Institute, the Foundation for the National Institutes of Health, and the United States Food and Drug Administration.
Tanja S. Zabka   +7 more
wiley   +1 more source

Extent and Incidence of Pseudo‐Worsening of Kidney Function Due to Oral Antitumor Therapeutics in the AMBORA Cohort: An Analysis of Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 802-811, March 2026.
A considerable number of oral antitumor therapeutics (OAT) has the potential for causing pseudo‐worsening of kidney function (PW) due to inhibition of renal creatinine secretion, i.e., kidney function is unaffected, while creatinine‐based calculation of glomerular filtration rate (eGFR) erroneously indicates an impaired kidney function.
Michael I. Sponfeldner   +13 more
wiley   +1 more source

Associations of Multimarkers of Metabolic Malnutrition and Inflammation With All‐Cause Mortality and Their Interplay With Thyroid Function

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
MVX, Thyroid Function and Mortality. ABSTRACT Introduction The metabolic vulnerability index (MVX)—a composite biomarker reflecting metabolic malnutrition and inflammation—has been linked to increased mortality risk in populations with cardiovascular disease.
Setor K. Kunutsor   +7 more
wiley   +1 more source

Effects of Curcumin/Turmeric Supplementation on Kidney Function in Individuals With Diabetes: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
This meta‐analysis of 12 randomised controlled trials (n = 1303) found that curcumin/turmeric supplementation significantly reduces serum urea levels in individuals with diabetes, but does not significantly affect creatinine, BUN, uric acid or albumin. The findings suggest a potential tubular benefit, though glomerular markers remain unchanged. Further
Hossein Bahari, Zahra Asadi
wiley   +1 more source

Strategies for Monitoring Serum Protein Degradation With an Antibody Array‐Based Technology

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
This study analyzed the stability of 480 proteins in human serum samples collected from 10 healthy donors and incubated at room temperature for 0–48 h. Antibody array profiling revealed significant time‐dependent degradation of 201 proteins. Subsequent physicochemical and functional enrichment analyses demonstrated that the degraded proteins were ...
Yanlin Wang   +7 more
wiley   +1 more source

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