Results 131 to 140 of about 33,345 (227)

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, Volume 59, Issue 8, August 2026.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Multi‐Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7416-7429, August 2026.
ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim, Salma Qassin, Lucy McKenna, Emma Hornsey, Dominic Italiano, Leonid Churilov, Richard J. MacIsaac, Jas‐mine Seah, Elif I. Ekinci, The Austin EMPA‐MRI Study Group   +9 more
wiley   +1 more source

Development and Validation of a Cystatin C-based Staging of AKI in Critically Ill Patients. [PDF]

Kidney Int Rep
Helmersson-Karlqvist J, Byberg L, Ärnlöv J, Bell M, Mårtensson J, Dardashti A, Svensson MK, Larsson A, Marks-Hultström M, Lipcsey M.   +9 more
europepmc   +1 more source

Early Hemolysis, Myolysis and Renal Stress Following Pentaspline Pulsed Field Versus Radiofrequency Ablation of Atrial Fibrillation

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Serial biomarker assessment in 40 patients undergoing first‐time pulmonary vein isolation showed greater hemolysis and myocardial myolysis after FARAPULSE pentaspline single‐shot pulsed field ablation than after radiofrequency ablation. Myoglobin changes were associated with transient changes in renal function, albeit these exploratory correlations do ...
Paul Felix Harbich, Lisa Auer, Florian Tinhofer, Achim Leo Burger, Tobias Eberl, Patrick Weltler, Stephan Dobner, Alexander Geppert, Kurt Huber, Christoph Clemens Kaufmann   +9 more
wiley   +1 more source

Real‐world clinical and laboratory changes after switching to two‐drug regimen in HIV‐suppressed individuals: 48 weeks and beyond

HIV Medicine, Volume 27, Issue 8, Page 1241-1252, August 2026.
Abstract Introduction Two‐drug regimens (2DRs) may reduce long‐term drug toxicities and drug‐drug interactions for people with HIV (PWH) on antiretroviral therapy (ART). This study evaluated clinical and laboratory outcomes in PWH who switched from standard ART to dolutegravir and lamivudine (DTG + 3TC) in real‐world settings.
Tommy Hing‐cheung Tang, Ruby Tsz‐shan Kwong, Phillip Chan, Kwok‐wai Lam, Helen Shuk‐ying Chan, Man‐yee Chu, Wilson Lam, Tak‐chiu Wu, Wai‐shing Leung, Sai‐kwong Yung, Wan‐man Ting, Annabel Kai‐tung Choy, Joe Lok‐fung Tung, Jason Ka‐wah Fong, Daniel Kai‐yeung Yeung, Man‐po Lee   +15 more
wiley   +1 more source

Comparison of Creatinine-, Cystatin C-, and Combined Creatinine-Cystatin C-Based Equations for Estimating Glomerular Filtration Rate: A Real-World Analysis in Patients with Chronic Kidney Disease. [PDF]

Int J Mol Sci
Osredkar J, Klemenčič I, Kumer K, Pajek J, Knap B.   +4 more
europepmc   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger, Rosemary A. Staniforth, Asbjorg Osk Snorradottir, Johnathan Cooper‐Knock, Kurt J. De Vos, J. Robin Highley   +5 more
wiley   +1 more source

Cystatin C regulates cell division in primary central nervous system lymphoma. [PDF]

Sci Rep
Koyama H, Nakajima K, Yamaguchi I, Enomoto N, Matsuda T, Kagusa H, Kitazato KT, Takagi Y.   +7 more
europepmc   +1 more source

Proteomic Dynamics of Ovine Allantoic and Amniotic Fluids During Gestation

Reproduction in Domestic Animals, Volume 61, Issue 8, August 2026.
ABSTRACT Gestational success in ruminants depends on the maintenance of a dynamic maternal–foetal microenvironment, resulting from complex interactions among the conceptus, extraembryonic membranes, maternal tissues, and gestational fluids. This study performed a comparative and longitudinal proteomic characterization of allantoic and amniotic fluids ...
Viviane Maria Codognoto, Rogério Araújo de Almeida Filho, Marcos Gomides Carvalho, Paula Zanin Rates, Flávio Augusto Lourencetti, Laiza Sartori de Camargo, Claudio Willian Delfes de Camargo, Juanita Valentina Guzmán Martínez, Luan Sitó da Silva, Eunice Oba   +9 more
wiley   +1 more source

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

Experimental Physiology, Volume 111, Issue 8, Page 3514-3524, 1 August 2026.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra   +2 more
wiley   +1 more source