Results 111 to 120 of about 34,990 (232)

Investigation of serum cystatin C levels and their diagnostic value in combination with inflammatory ratios in patients with bipolar disorder

Frontiers in Psychiatry
BackgroundIt is thought that inflammation significantly contributes to the development of bipolar disorder (BD), and recent findings indicate a connection between cystatin C and immune-related inflammation. In this study, we investigated serum cystatin C
Chenjiao Zhang, Chenjiao Zhang, Jinbao Ma, Huanqin Gao, Yanhong Luo, Junhui Feng, Yanyan Wei, Jingxu Chen   +7 more
doaj   +1 more source

Microglial Labeling in Mouse Spinal Cord Injury: A Review of Timing, Efficacy, and Specificity

Glia, Volume 74, Issue 12, December 2026.
The transcriptional profile of microglia is significantly altered after spinal cord injury (SCI). When choosing a marker to label microglia after SCI, it is important to consider its specificity for microglia and its stability of expression. ABSTRACT Traumatic spinal cord injury (SCI) is a complex and disabling condition with no curative therapy ...
Ruth Colbert, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, Volume 123, Issue 11, Page 3079-3105, November 2026.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

MedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu, Shuting Chen, Weijia Zhao, Dake Di, Jiao Liu, Yuyang Tian, Yurong Luo, Yingping Xu, Ruzeng Xue, Li Ye, Xiaoping Pei, Bihui Yu, Yu Wang, Jiao Zhang, Xiaoling Yu, Wei Wen, Liyan Yuan, Suyun Ji, Claire Hu, Dan Shen, Yiqing Guo, Yunsheng Liang   +21 more
wiley   +1 more source

Association of Neutrophil Percentage‐to‐Albumin Ratio (NPAR) With Pathological Features and Long‐Term Prognosis in Diabetic Kidney Disease: A Cohort Study

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This graphical abstract summarizes the association between the neutrophil percentage‐to‐albumin ratio (NPAR), renal pathology, and prognosis in biopsy‐confirmed diabetic kidney disease. Higher NPAR was associated with increased renal MPO‐positive neutrophil infiltration, more severe histopathological injury, and poorer renal outcomes.
Yang Li, Hongyu Wang, Wendi He, Yi Fang, Shi Jin, Hong Liu, Jie Li, Nana Song, Xiaoqiang Ding, Yan Dai   +9 more
wiley   +1 more source

Urinary symmetric dimethylarginine: A promising biomarker for acute kidney injury in dogs with pyometra

Veterinary Record, Volume 199, Issue 7, Page e337-e344, 3/10 October 2026.
Abstract Background Symmetric dimethylarginine (SDMA) is a biomarker of renal function derived from arginine methylation, unaffected by muscle mass or diet, and increases after only a 25% reduction in renal function, allowing earlier detection of renal dysfunction compared with serum creatinine.
Larissa Ayane do Nascimento Braz, Suellen Rodrigues Maia, Lara Vilela Soares, Natani Silva Reis, Leandro Zuccolotto Crivellenti, Andrigo Barboza de Nardi   +5 more
wiley   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Cystatin-C [PDF]

, 2020
openaire   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

Experimental Physiology, EarlyView.
Anders Møller Greve, Anna Agnes Lytzen, Hrefna Sæunn Einarsdóttir, Michael Perch, Ronan M. G. Berg   +4 more
wiley   +1 more source