Results 111 to 120 of about 33,345 (227)

Squash silverleaf disorder and whitefly (Bemisia tabaci MEAM1) infestation: Implications for plant disease management in a changing climate

Annals of Applied Biology, Volume 189, Issue 2, September 2026.
Squash Silverleaf Disorder (SLD) is growing in its economic impact due to the invasive behaviour of the silverleaf whitefly (Bemisia tabaci MEAM1). In this review we summarize what is currently known about the whitefly‐squash interaction, how both the disease and the whitefly are being affected by climate change, and discuss current and novel ...
Nihal Oztolan‐Erol, Yusuf Sen, Melike Cokol‐Cakmak, Guler Demirbas‐Uzel, Stuart J. Lucas   +4 more
wiley   +1 more source

Hepatic Safety of Orforglipron in Adults With Obesity or Overweight and/or Type 2 Diabetes: A Pooled Analysis of the Orforglipron Phase 3 Clinical Trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8347-8358, September 2026.
ABSTRACT Aims Orforglipron is a novel small‐molecule, once daily oral non‐peptide GLP‐1 receptor agonist. The hepatic safety profile in adults with obesity or overweight and/or type 2 diabetes (T2D) across seven orforglipron Phase 3 clinical trials was assessed.
Sean Wharton, Adam Stefanski, Jiaxun Chen, Girish Rao, Elvis Asare Twum, Max Denning   +5 more
wiley   +1 more source

NbRD21 protease controls receptor kinase homeostasis in Nicotiana benthamiana

New Phytologist, Volume 251, Issue 5, Page 2741-2752, September 2026.
Proteomic analysis revealed that receptor kinases (red) accumulate higher in rd21 knockout Nicotiana benthamiana plants. Summary RD21‐like proteases are papain‐like cysteine proteases with a C‐terminal granulin domain that are abundant and ubiquitous in angiosperms and have often been implicated in immunity.
Alice Godson, Lauren Eddie, Mariana Schuster, Kaijie Zheng, Reka Toth, Yuge Li, Tianrun Li, Jie Huang, Farnusch Kaschani, Philippe V. Jutras, Jiorgos Kourelis, Markus Kaiser, Tolga Bozkurt, Renier A. L. Van der Hoorn   +13 more
wiley   +1 more source

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song, Xiaoqun Liu, Tianrui Yu, Yuanyuan Xiang, Peijie Fu, Moxin Wu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen   +8 more
wiley   +1 more source

Probing effect modification by socioeconomic status in associations between blood biomarkers of neuropathology and cognitive outcomes in the United States and India

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Socioeconomic factors influence cognitive outcomes and may modify associations between neuropathologies and cognitive outcomes, yet evidence from low‐ and middle‐income contexts remains scarce. METHODS We used harmonized data from nationally representative studies in the United States (Health and Retirement Study ‐ Harmonized ...
Emma Nichols, Jung Ki Kim, Leon M. Aksman, Alden L. Gross, Peifeng Hu, Lindsay C. Kobayashi, Bharat Thyagarajan, Jinkook Lee, Eileen M. Crimmins   +8 more
wiley   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 465-474, August 2026.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur, Jashvant D. Unadkat, Emily E. Fay, Nina Isoherranen, Mary F. Hebert   +4 more
wiley   +1 more source

On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur

Experimental Physiology, EarlyView.
Anders Møller Greve, Anna Agnes Lytzen, Hrefna Sæunn Einarsdóttir, Michael Perch, Ronan M. G. Berg   +4 more
wiley   +1 more source

Nanomaterial‐Based CRISPR/Cas‐Powered Electrochemical Sensing Integrated With Microfluidics for Rapid and Sensitive Diagnostics

Electrochemical Science Advances, Volume 6, Issue 4, August 2026.
ABSTRACT Rapid and sensitive detection of disease‐related biomarkers is critical for early diagnosis and appropriate treatment. However, conventional analytical methods are often time‐consuming and require complex procedures and skilled personnel.
Minju Ahn, Sang Baek Sim, Izzati Haizan, Jin‐Ha Choi, Jeong‐Woo Choi   +4 more
wiley   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, Volume 101, Issue 9, Page 2430-2434, September 2026.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

Network Pharmacology Combined With Metabonomics and Transcriptomics Reveals the Mechanism of Rubus Chingii Hu in Alleviating Nephrotoxicity Caused by Tripterygium Glycosides Tablet

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Flow chart of RCH to improve TGT‐induced nephrotoxicity. ABSTRACT Researches on Tripterygium glycosides tablets (TGT) often overlook renal toxicity from prolonged use. Rubus chingii Hu (RCH) is beneficial to kidney health and has an unclear role in reducing nephrotoxicity.
Cong Zhang, Zepeng Zhang, Tong Zhou, Lei Zhang   +3 more
wiley   +1 more source