Results 141 to 150 of about 34,990 (232)

Oxidative Stress Drives Cell Cycle Stalling, Apoptosis and Metabolic Suppression in Cystatin B Deficient EPM1 Patient iPSCs

open access: yesCell Proliferation, Volume 59, Issue 10, October 2026.
CSTB deficient EPM1 iPS cells manifest increased lysosomal activity and oxidative stress, which lead to DNA damage, cell cycle defects and increased apoptosis. As a protective response, metabolism is suppressed. Image created by BioRender https://BioRender.com/t44oc6h.
Shekhar Singh   +4 more
wiley   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis. [PDF]

open access: yesNeuropathol Appl Neurobiol
Granger SM   +5 more
europepmc   +1 more source

Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9054-9068, October 2026.
ABSTRACT Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real‐world associations between a telehealth‐delivered, individualized nutrition therapy program (VINT) and CKD incidence and progression compared with usual ...
Shaminie J. Athinarayanan   +7 more
wiley   +1 more source

Glomerular filtration rate estimation in nephrotic patients: creatinine and/or cystatin-C-based equations, or none of them? [PDF]

open access: yesClin Kidney J
Carrara F   +12 more
europepmc   +1 more source

Feasibility of Decentralised Response‐Guided Albuminuria Monitoring to Optimise Empagliflozin and Finerenone Therapy in Type 2 Diabetes and Chronic Kidney Disease

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9412-9422, October 2026.
ABSTRACT Aims To assess the feasibility of a decentralised response‐guided trial and to characterise urinary albumin‐to‐creatinine ratio (UACR) responses to empagliflozin and finerenone in type 2 diabetes and chronic kidney disease (CKD). Materials and Methods Adults with type 2 diabetes, estimated glomerular filtration rate (eGFR) ≥ 25 mL/min/1.73 m2,
Jelle M. Beernink   +2 more
wiley   +1 more source

Simple Bedside Muscle‐Related Indicators Improve the Identification of Reduced Kidney Function in Hospitalized Older Adults: A Multicenter Cross‐Sectional Study

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 10, October 2026.
Adding simple bedside muscle‐related indicators (calf circumference or the finger‐ring test) to creatinine‐based kidney function assessment improved the identification of reduced kidney function defined by cystatin C in hospitalized older adults. These measures may complement interpretation of eGFRcr in routine clinical practice.
Shigemi Morishita   +5 more
wiley   +1 more source

Combined sleep behaviors, mediating biomarkers, and incident vascular complications among individuals with type 2 diabetes: A prospective study in UK Biobank

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 10, Page 1782-1793, October 2026.
Among UK Biobank participants with type 2 diabetes, combined healthy sleep behaviors were associated with lower risks of vascular complications. Lipid and inflammatory biomarkers partially mediated these associations. ABSTRACT Aims To prospectively examine how combined sleep behaviors affect vascular complications in type 2 diabetes, whether these ...
Yanqiu Zou   +18 more
wiley   +1 more source

Study variation in estimating Glomerular Filtration Rate (GFR) from serum creatinine, cystatin C, age, and sex. [PDF]

open access: yesPLoS One
Fino N   +6 more
europepmc   +1 more source

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