Results 81 to 90 of about 34,990 (232)

Bee pollen as functional food and environmental bioindicator: current evidence and future challenges

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Bee pollen (BP), a plant‐derived product collected by honey bees, is increasingly promoted as a functional food due to its content of proteins, essential amino acids, lipids, vitamins, minerals, and bioactive compounds such as polyphenols and flavonoids.
Luigi Parrotta, Stefano Del Duca
wiley   +1 more source

Cystatin C: A prognostic marker after myocardial infarction in patients without chronic kidney disease

Journal of the Saudi Heart Association, 2016
Aims: Cystatin C is an endogenous marker of renal function. It is a well established better marker of glomerular filtration rate than serum creatinine. There is also evidence that cystatin C is associated with atherosclerotic disease.
Leila Abid, Salma Charfeddine, Samir Kammoun, Mouna Turki, Fatma Ayedi   +4 more
doaj   +1 more source

Cystatin C for Therapeutic Drug Monitoring

Clinical Chemistry, 2015
A 78-year-old man with prostate cancer needed intravenous treatment with amikacin for a suspected gram-negative bacillary respiratory infection. He had a body surface area of 1.97 m2, weight of 78 kg, and body mass index of 29 kg/m2. Laboratory test results are shown in Table 1. Because the initial renal function was judged to be normal and the patient
Noemí, Rebollo, Francisco Javier, Cepeda-Piorno   +1 more
openaire   +2 more sources

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Cystatin C as a Biomarker for Identifying High-Risk Patients with Acute Coronary Syndrome: An Observational Study

Clinical and Applied Thrombosis/Hemostasis
Background Cystatin C is a cysteine protease inhibitor, synthesized by nucleated cells, and released into various body fluids. Lots of studies have reported an association between cystatin C and atherosclerotic cardiovascular disease.
Xinlin Xiong MD, Li Yuan MB, Xiaobin Long MM, Minsheng An MB, Shen Huang MM, Liang Liu MB   +5 more
doaj   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Rapid Outpatient Tube Weaning Is Effective but Associated With Frequent Adverse Events: A Retrospective Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To evaluate the outcomes and safety of an outpatient tube‐weaning programme involving rapid tube feed reduction. Methods This retrospective patient record‐based cohort study included children referred to a multidisciplinary, hunger provocation‐based tube‐weaning programme from 2016 to 2023 in our tertiary paediatric hospital.
Josefine Limnell, Mari Ahlroos, Maisa Keski‐Kuha, Päivi Peldan, Jetta Tuokkola, Anna Kaarina Kukkonen, Laura Merras‐Salmio   +6 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Cystatin C proteoforms in chronic kidney disease

PLoS ONE, 2023
Cystatin C, a cysteine protease inhibitor, is used as a biomarker of renal function. It offers several advantages compared to creatinine, and formulas for the estimation of the glomerular filtration rate based on cystatin C have been developed. Recently,
Helene Dahl, Klaus Meyer, Kristina Sandnes, Natasha Lervaag Welland, Iselin Arnesen, Hans-Peter Marti, Jutta Dierkes, Vegard Lysne   +7 more
doaj  

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source