Results 131 to 140 of about 827,600 (338)

The Functional Significance of High Cysteine Content in Eye Lens γ-Crystallins

open access: yesBiomolecules
Cataract disease is strongly associated with progressively accumulating oxidative damage to the extremely long-lived crystallin proteins of the lens. Cysteine oxidation affects crystallin folding, interactions, and light-scattering aggregation especially
Eugene Serebryany   +2 more
doaj   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

Dual-topology insertion of a dual-topology membrane protein. [PDF]

open access: yes, 2015
Some membrane transporters are dual-topology dimers in which the subunits have inverted transmembrane topology. How a cell manages to generate equal populations of two opposite topologies from the same polypeptide chain remains unclear.
Bowie, James U   +2 more
core  

Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation

open access: yesAdvanced Healthcare Materials, EarlyView.
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng   +5 more
wiley   +1 more source

Statistic evaluation of cysteine and allyl alcohol as additives for Cu-Zn coatings from citrate baths

open access: yesMaterials Research, 2013
In the present work, cysteine and allyl alcohol were added to citrate baths as additives to Cu-Zn coatings on steel substrates. In order to verify the effects of the deposition parameters (current density, mechanical stirring speed, and additives) on the
Julyana Ribeiro Garcia   +5 more
doaj  

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li   +7 more
wiley   +1 more source

Surface Plasmon Resonance Enhanced Photoelectrochemical Sensing of Cysteine Based on Au Nanoparticle-Decorated ZnO@graphene Quantum Dots

open access: yesMolecules
In this work, Au nanoparticle-decorated ZnO@graphene core–shell quantum dots (Au-ZnO@graphene QDs) were successfully prepared and firstly used to modify an ITO electrode for the construction of a novel photoelectrochemical biosensor (Au-ZnO@graphene QDs ...
Jiaxin Liu, Fancheng Lin, Yan Wang
doaj   +1 more source

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

open access: yesAdvanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra   +7 more
wiley   +1 more source

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