Results 171 to 180 of about 589,705 (297)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome [PDF]

open access: bronze, 2012
Paula J. Hurley   +16 more
openalex   +1 more source

A Water‐Soluble PVA Macrothiol Enables Two‐Photon Microfabrication of Cell‐Interactive Hydrogel Structures at 400 mm s−1

open access: yesAdvanced Materials, EarlyView.
A PVA‐based macromolecular thiol‐ene formulation enables efficient two‐photon polymerization at extremely low polymer concentrations and high writing speeds of 400 mm s−1 (20×), allowing high‐fidelity laser writing of cell‐interactive hydrogel structures on demand.
Wanwan Qiu   +6 more
wiley   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

open access: yesAdvanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park   +13 more
wiley   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

open access: yesAdvanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy