Results 221 to 230 of about 589,705 (297)
Cysteine S-acetylation is a widespread post-translational modification on metabolic proteins. [PDF]
Keenan EK +4 more
europepmc +1 more source
Structure-Guided Design of Novel
Naohisa Ogo +5 more
openalex +1 more source
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu +23 more
wiley +1 more source
Structure-Functional Examination of Cysteine Synthase A (CysK) from <i>Limosilactobacillus reuteri</i> LR1. [PDF]
Pometun AA +16 more
europepmc +1 more source
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source
Regulating the orientation of homobivalent small binders through 3D domain-swapping design. [PDF]
Shiga S, Watanabe H, Makabe K, Honda S.
europepmc +1 more source
Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo +11 more
wiley +1 more source
A Highly Reactive Cysteine-Targeted Acrylophenone Chemical Probe That Enables Peptide/Protein Bioconjugation and Chemoproteomics Analysis. [PDF]
Nuber CM +13 more
europepmc +1 more source

