Results 21 to 30 of about 183,470 (243)

Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases [PDF]

FEBS Letters, 1998
Jinq-May Chen, N. Rawlings, Richard A. E. Stevens, A. Barrett   +3 more
semanticscholar   +2 more sources

The role of lysosomal peptidases in glioma immune escape: underlying mechanisms and therapeutic strategies

Frontiers in Immunology, 2023
Glioblastoma is the most common primary malignant tumor of the central nervous system, which has the characteristics of strong invasion, frequent recurrence, and rapid progression.
Hao Liu, Hao Liu, Jie Peng, Jie Peng, Linzhen Huang, Dong Ruan, Yuguang Li, Fan Yuan, Zewei Tu, Zewei Tu, Zewei Tu, Zewei Tu, Kai Huang, Kai Huang, Kai Huang, Kai Huang, Xingen Zhu, Xingen Zhu, Xingen Zhu, Xingen Zhu   +19 more
doaj   +1 more source

Frozen fresh blood plasma preserves the functionality of native human α2-macroglobulin

Scientific Reports, 2023
Human α2-macroglobulin (hα2M) is a large homotetrameric protein involved in the broad inhibition of endopeptidases. Following cleavage within a bait region, hα2M undergoes stepwise transitions from its native, expanded, highly flexible, active ...
Soraia R. Mendes, F. Xavier Gomis-Rüth, Theodoros Goulas   +2 more
doaj   +1 more source

Plant-Programmed Cell Death-Associated Genes Participation in Pinus sylvestris L. Trunk Tissue Formation

Plants, 2022
Molecular genetic markers of various PCD (programmed cell death) variants during xylo- and phloemogenesis have been identified for the first time in Scots pine under lingonberry pine forest conditions in Northwest Russia (middle taiga subzone).
Yulia L. Moshchenskaya, Natalia A. Galibina, Kseniya M. Nikerova, Tatiana V. Tarelkina, Maksim A. Korzhenevsky, Irina N. Sofronova, Maria A. Ershova, Ludmila I. Semenova   +7 more
doaj   +1 more source

Anti-Fungal Hevein-like Peptides Biosynthesized from Quinoa Cleavable Hololectins

Molecules, 2021
Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally synthesized peptides that are known to be bioprocessed from the following
Shining Loo, Stephanie V. Tay, Antony Kam, Fan Tang, Jing-Song Fan, Daiwen Yang, James P. Tam   +6 more
doaj   +1 more source

Abstract 1598 Targeting prolyl endopeptidase with cysteine-reactive covalent inhibitors

Journal of Biological Chemistry
Ian Fucci, Kalyani Thakur, Joshua Pandian, Lixin Fan, Euna Yoo, Diana Monteiro   +5 more
openaire   +3 more sources

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

Frontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu, Yiqun Jia, Xiaobing Chen, Haoyu Li, Zhi Wang, Bin Cheng   +5 more
doaj   +1 more source

A Boophilus microplus vitellin-degrading cysteine endopeptidase [PDF]

Parasitology, 2003
Here we describe the purification and characterization of a vitellin (VT) degrading cysteine endopeptidase (VTDCE) from eggs of the hard tick Boophilus microplus. A homogeneous enzyme preparation was obtained by chromatographic fractionation on ion-exchange and gel filtration columns and an autolysis step.
A, Seixas, P C, Dos Santos, F F, Velloso, I, Da Silva Vaz, A, Masuda, F, Horn, C, Termignoni   +6 more
openaire   +2 more sources

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases.

PLoS ONE, 2020
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological
Michele S Y Tan, Dara Davison, Mateo I Sanchez, Bethany M Anderson, Stephen Howell, Ambrosius Snijders, Laura E Edgington-Mitchell, Edgar Deu   +7 more
doaj   +1 more source

Functional and Bioactive Properties of Wheat Protein Fractions: Impact of Digestive Enzymes on Antioxidant, α-Amylase, and Angiotensin-Converting Enzyme Inhibition Potential

Molecules, 2023
This research aimed to determine the biofunctional properties of wheat flour (WF) protein fractions and modifications to the antioxidant, anti-α-amylase and anti-angiotensin-I converting enzyme (ACE) activities induced by the action of digestive ...
Sana Gammoh, Muhammad H. Alu’datt, Mohammad N. Alhamad, Carole C. Tranchant, Taha Rababah, Doa’a Al-U’datt, Neveen Hussein, Mohammad Alrosan, Thuan-Chew Tan, Stan Kubow, Haya Alzoubi, Ali Almajwal   +11 more
doaj   +1 more source