Results 21 to 30 of about 277 (144)

Plant-Programmed Cell Death-Associated Genes Participation in Pinus sylvestris L. Trunk Tissue Formation

open access: yesPlants, 2022
Molecular genetic markers of various PCD (programmed cell death) variants during xylo- and phloemogenesis have been identified for the first time in Scots pine under lingonberry pine forest conditions in Northwest Russia (middle taiga subzone).
Yulia L. Moshchenskaya   +7 more
doaj   +1 more source

Anti-Fungal Hevein-like Peptides Biosynthesized from Quinoa Cleavable Hololectins

open access: yesMolecules, 2021
Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally synthesized peptides that are known to be bioprocessed from the following
Shining Loo   +6 more
doaj   +1 more source

Functional and Bioactive Properties of Wheat Protein Fractions: Impact of Digestive Enzymes on Antioxidant, α-Amylase, and Angiotensin-Converting Enzyme Inhibition Potential

open access: yesMolecules, 2023
This research aimed to determine the biofunctional properties of wheat flour (WF) protein fractions and modifications to the antioxidant, anti-α-amylase and anti-angiotensin-I converting enzyme (ACE) activities induced by the action of digestive ...
Sana Gammoh   +11 more
doaj   +1 more source

Comparative proteome analysis of the ligamentum flavum of patients with lumbar spinal canal stenosis

open access: yesJOR SPINE, Volume 5, Issue 4, December 2022., 2022
This study investigated the pathology of thickened ligamentum flavum in patients with lumbar spinal canal stenosis (LSCS) based on protein expression levels using shotgun proteome analysis. The results showed that tissue repair via fibrosis, chondrometaplasia, and amyloid deposits may be important pathologies that occur in the thickened ligamentum ...
Yutaka Yabe   +8 more
wiley   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu   +5 more
doaj   +1 more source

The Structure and Organization of Two Cysteine Endopeptidase Genes from Rice [PDF]

open access: yesPlant and Cell Physiology, 1999
REP-1 is a major cysteine endopeptidase that digests seed storage glutelin of rice. A cDNA clone (pRP60) for REP-1 and a cDNA clone (pRP80) for a related enzyme were previously isolated. The expression of both mRNAs is regulated by gibberellin. In this study, we revealed the structure and organization of Rep1 and RepA, genes corresponding to pRP60 and ...
Hideki Kato   +2 more
openaire   +3 more sources

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases.

open access: yesPLoS ONE, 2020
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological
Michele S Y Tan   +7 more
doaj   +1 more source

Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population

open access: yesEuropean Journal of Neurology, Volume 30, Issue 2, Page 434-442, February 2023., 2023
Polygenic risk for MS associates with changes in the peripheral B‐cell compartment of children in the general population. A MS‐PRS was significantly associated with lower relative, but not absolute, naive B‐cell numbers and higher frequencies and absolute numbers of CD27+ memory B cells.
Casper L. de Mol   +8 more
wiley   +1 more source

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases.

open access: yesPLoS ONE, 2017
Allosteric targeting is progressively gaining ground as a strategy in drug design. Its success, however, depends on our knowledge of the investigated system.
Marko Novinec
doaj   +1 more source

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