Results 41 to 50 of about 277 (144)
Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots [PDF]
PLoS Comput Biol 5(10): e1000547 (2009), 2009 A new theoretical survey of proteins' resistance to constant speed stretching is performed for a set of 17 134 proteins as described by a structure-based model. The proteins selected have no gaps in their structure determination and consist of no more than 250 amino acids.
arxiv +1 more source
Veterinary Research, 2019 Yersinia ruckeri is the causative agent of enteric redmouth disease in salmonids. In fish, the intestine represents an important site of nutrient uptake, host–pathogen interactions, and defense.
Gokhlesh Kumar +3 more
doaj +1 more source
Proteomes, 2018 The recent identification of catalytically active peptidylglycine α-amidating monooxygenase (PAM) in Chlamydomonas reinhardtii, a unicellular green alga, suggested the presence of a PAM-like gene and peptidergic signaling in the last eukaryotic ...
Raj Luxmi +6 more
doaj +1 more source
Benzophenone Semicarbazones as Potential alpha-glucosidase and Prolyl Endopeptidase Inhibitor: In-vitro free radical scavenging, enzyme inhibition, mechanistic, and molecular docking studies [PDF]
arXiv, 2023 $\alpha$-glucosidase and prolylendopeptidase has altered expression and activity patterns in neurological disease, type 2diabetes respectively and several cancers. Here we screened a series 1-29 benzophenone semicarbazone derivatives for in vitro free radical scavenging, alpha-glucosidase and prolylendopeptidase inhibition activities. Seven derivatives
arxiv
Angewandte Chemie, EarlyView.Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka +5 more
wiley +2 more sources
About thiol derivatization and resolution of basic proteins in two-dimensional electrophoresis [PDF]
Proteomics 4 (03/2004) 551-61, 2006 The influence of thiol blocking on the resolution of basic proteins by two-dimensional electrophoresis was investigated. Cysteine blocking greatly increased resolution and decreased streaking, especially in the basic region of the gels. Two strategies for cysteine blocking were found to be efficient: classical alkylation with maleimide derivatives and ...
arxiv +1 more source
Senescence in wheat leaves: is a cysteine endopeptidase involved in the degradation of the large subunit of Rubisco? [PDF]
Acta Physiologiae Plantarum, 2007 In wheat (Triticum aestivum L.), leaf senescence can be initiated by different factors. Depending on the plant system (intact plants or detached leaves) or the environmental conditions (light, nutrient availability), the symptoms of senescence differ.
Thoenen, Melanie +2 more
openaire +4 more sources
Overcharging of zinc ion in the structure of zinc finger protein is needed for DNA binding stability [PDF]
, 2019 The zinc finger structure where a Zn2+ ion binds to 4 cysteine or histidine amino acids in a tetrahedral structure is very common motif of nucleic acid binding proteins. The corresponding interaction model is present in 3% of the genes of human genome.
arxiv +1 more source
THz spectroscopy on amino acids [PDF]
J. Chem. Phys. 160 (2024) 145103, 2023 We present a detailed study on the temperature-dependent THz spectra of the polycrystalline amino acids L-serine and L-cysteine for wave numbers from 20 to 120 cm-1 and temperatures from 4 to 300 K. Even though the structure of these two amino acids is very similar, with a sulfur atom in the side chain of cysteine instead of an oxygen atom in serine ...
arxiv
Investigation of the impact of PTMs on the protein backbone conformation [PDF]
Amino Acids, Springer Verlag, 2019, 51 (7), pp.1065-1079, 2019 Post-Translational Modifications (PTMs) are known to play a critical role in the regulation of the protein functions. Their impact on protein structures, and their link to disorder regions have already been spotted on the past decade. Nonetheless, the high diversity of PTMs types, and the multiple schemes of protein modifications (multiple PTMs, of ...
arxiv +1 more source