Results 81 to 90 of about 277 (144)

Optoelectronic properties of a photosystem I - carbon nanotube hybrid system [PDF]

open access: yes, 2009
The photoconductance properties of photosystem I (PSI) covalently bound to carbon nanotubes (CNTs) are measured. We demonstrate that the PSI forms active electronic junctions with the CNTs enabling control of the CNTs photoconductance by the PSI. In order to electrically contact the photoactive proteins, a cysteine mutant is generated at one end of the
arxiv   +1 more source

Preascitic Sodium Retention in Cirrhosis: A Role for Disregulated Proteolysis by Proprotein Convertases?

open access: yesLiver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT Loss of effective arterial blood volume, secondary hyperaldosteronism, adrenergic activation and nonosmotic hypersecretion of vasopressin induce sodium and water retention in cirrhotic patients with ascites. The mechanisms of sodium retention that precede ascites formation remain elusive.
Giovanni Sansoè   +2 more
wiley   +1 more source

Cyclization of the Analgesic α‐Conotoxin Vc1.1 With a Non‐Natural Linker: Effects on Structure, Stability, and Bioactivity

open access: yesJournal of Peptide Science, Volume 31, Issue 6, June 2025.
This study cyclized conotoxin Vc1.1 using polyethylene glycol (PEG) linkers of different lengths and demonstrates that linker length modulates the peptide's helicity, thereby influencing its biological activity and stability. ABSTRACT α‐Conotoxin Vc1.1 is a disulfide‐rich peptide and a promising drug candidate for treating neuropathic and chronic pain.
Yuhui Zhang   +4 more
wiley   +1 more source

Genetic and transcriptomic analysis of lentil seed imbibition and dormancy in relation to its domestication

open access: yesThe Plant Genome, Volume 18, Issue 2, June 2025.
Abstract Seed dormancy is an adaptation that delays germination to prevent the start of this process during unsuitable conditions. It is crucial in wild species but its loss was selected during crop domestication to ensure a fast and uniform germination. Water uptake, or imbibition, is the first step of germination.
Azalea Guerra‐García   +5 more
wiley   +1 more source

Hybrid gold single crystals incorporating amino acids [PDF]

open access: yesarXiv, 2016
Composite hybrid gold crystals are of profound interest in various research areas ranging from materials science to biology. Their importance is due to their unique properties and potential implementation, for example in sensing or in bio-nanomedicine. Here we report on the formation of hybrid organic-metal composites via the incorporation of selected ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1203-1221, May 2025.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Fe(3+)-eta(2)-peroxo species in superoxide reductase from Treponema pallidum. Comparison with Desulfoarculus baarsii [PDF]

open access: yesBiophysical Chemistry, Elsevier, 2006, pp.38-48, 2015
Superoxide reductases (SORs) are superoxide (O2-)-detoxifying enzymes that catalyse the reduction of O2- into hydrogen peroxide. Three different classes of SOR have been reported on the basis of the presence or not of an additional N-terminal domain. They all share a similar active site, with an unusual non-heme Fe atom coordinated by four equatorial ...
arxiv  

Folding of Cu, Zn superoxide dismutase and Familial Amyotrophic Lateral Sclerosis [PDF]

open access: yesarXiv, 2003
Cu,Zn superoxide dismutase (SOD1) has been implicated in the familial form of the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS). It has been suggested that mutant mediated SOD1 misfolding/aggregation is an integral part of the pathology of ALS.
arxiv  

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