Results 1 to 10 of about 4,793 (98)

Purification and characterization of cysteine protease of Sarcocystis fusiformis from infected Egyptian water buffaloes

Scientific Reports, 2023
Sarcocystis spp. infects water buffaloes (Bubalus bubalis) causing sarcocystosis. In the present study, Sarcocystis fusiformis was recognized in Egyptian water buffaloes based on histological observation and molecular analysis of internal transcribed ...
Amal Z. Barakat, Azza M. Abdel-Aty, Marwa K. Ibrahim, Hala A. Salah, Usama M. Hegazy, Rasha A. M. Azouz, Roqaya I. Bassuiny, Raafat M. Shaapan, Saleh A. Mohamed   +8 more
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Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion. [PDF]

PLoS Pathogens, 2006
Erythrocytic malaria parasites utilize proteases for a number of cellular processes, including hydrolysis of hemoglobin, rupture of erythrocytes by mature schizonts, and subsequent invasion of erythrocytes by free merozoites.
Kailash C Pandey, Naresh Singh, Shirin Arastu-Kapur, Matthew Bogyo, Philip J Rosenthal   +4 more
doaj   +1 more source

Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. [PDF]

PLoS Medicine, 2007
Schistosomiasis is a chronic, debilitating parasitic disease infecting more than 200 million people and is second only to malaria in terms of public health importance.
Maha-Hamadien Abdulla, Kee-Chong Lim, Mohammed Sajid, James H McKerrow, Conor R Caffrey   +4 more
doaj   +1 more source

Determination the binding ability of N-acetyl cysteine and its derivatives with SARS-COV-2 main protease using molecular docking and molecular dynamics studies [PDF]

The Ukrainian Biochemical Journal, 2021
N-acetyl cysteine (NAC) drug has been used as an antioxidant and anti-inflammatory agent in clinical practice and more recently in the treatment of COVID-19 patients.
A. H. Shntaif, N. A. Alrazzak, A. Bader, A. M. Almarzoqi   +3 more
doaj   +1 more source

Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9

Frontiers in Plant Science, 2022
The hypersensitive response is elicited by Agrobacterium infiltration of Nicotiana benthamiana, including the induction and accumulation of pathogenesis-related proteins, such as proteases.
Advaita Acarya Singh, Advaita Acarya Singh, Priyen Pillay, Previn Naicker, Kabamba Alexandre, Kanyane Malatji, Lukas Mach, Herta Steinkellner, Juan Vorster, Rachel Chikwamba, Tsepo L. Tsekoa   +10 more
doaj   +1 more source

Cohnella 1759 cysteine protease shows significant long term half-life and impressive increased activity in presence of some chemical reagents

Scientific Reports, 2021
Thermostability and substrate specificity of proteases are major factors in their industrial applications. rEla is a novel recombinant cysteine protease obtained from a thermophilic bacterium, Cohnella sp.A01 (PTCC No: 1921).
Rayan Saghian, Elham Mokhtari, Saeed Aminzadeh   +2 more
doaj   +1 more source

Schistosoma japonicum cathepsin B2 (SjCB2) facilitates parasite invasion through the skin.

PLoS Neglected Tropical Diseases, 2020
Cercariae invasion of the human skin is the first step in schistosome infection. Proteases play key roles in this process. However, little is known about the related hydrolytic enzymes in Schistosoma japonicum.
Bingkuan Zhu, Fang Luo, Yi Shen, Wenbin Yang, Chengsong Sun, Jipeng Wang, Jian Li, Xiaojin Mo, Bin Xu, Xumin Zhang, Yongdong Li, Wei Hu   +11 more
doaj   +1 more source

The Cysteine Protease–Cysteine Protease Inhibitor System Explored in Soybean Nodule Development

Agronomy, 2013
Almost all protease families have been associated with plant development, particularly senescence, which is the final developmental stage of every organ before cell death.
Marian Dorcas Quain, Karl Kunert, Christine Helen Foyer, Ignatious Ncube, Matome Eugene Makgopa, Stefan van Wyk, Magdeleen du Plessis, Urte Schlüter, Barend Juan Vorster   +8 more
doaj   +1 more source

cDNA cloning and molecular modeling of procerain B, a novel cysteine endopeptidase isolated from Calotropis procera. [PDF]

PLoS ONE, 2013
Procerain B, a novel cysteine protease (endopeptidase) isolated from Calotropis procera belongs to Asclepiadaceae family. Purification of the enzyme, biochemical characterization and potential applications are already published by our group.
Abhay Narayan Singh, Prity Yadav, Vikash Kumar Dubey   +2 more
doaj   +1 more source

C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule

Nature Communications, 2023
The precise modification or functionalization of the protein C-terminus is essential but full of challenges. Herein, a chemical approach to modify the C-terminus is developed by fusing a cysteine protease domain on the C-terminus of the protein of ...
Yue Zeng, Wei Shi, Zhi Liu, Hao Xu, Liya Liu, Jiaying Hang, Yongqin Wang, Mengru Lu, Wei Zhou, Wei Huang, Feng Tang   +10 more
doaj   +1 more source