Results 211 to 220 of about 313,172 (330)

Activation of a 66-kilodalton human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease [PDF]

, 1996
Eugene H. Burns, Ann Marie Marciel, James M. Musser   +2 more
openalex   +1 more source

Irreversible Inhibitors of Cysteine Proteases [PDF]

ACS Medicinal Chemistry Letters, 2013
openaire   +2 more sources

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Comparative analysis of cysteine protease nano-formulations to manage callosobruchus maculatus fabricius and trogoderma granarium everts in stored products. [PDF]

Sci Rep
Ahmad S, Akrem A, Najam-Ul-Haq M, Mehmood S, Batool M, Saeed A, Jabeen F, Ashraf S, Bashir N, Saeed Q.   +9 more
europepmc   +1 more source

Inhibition of cysteine proteases by a natural biflavone: behavioral evaluation of fukugetin as papain and cruzain inhibitor

, 2012
Diego M. Assis, Vanessa Silva Gontijo, Ivan de Oliveira Pereira, Jorge A.N. Santos, Ihosvany Camps, Tânus Jorge Nagem, Javier Ellena, Mario Augusto Izidoro, Ivarne L.S. Tersariol, Nilana M.T. Barros, A.C. Doriguetto, Marcelo Henrique dos Santos, María A. Juliano   +12 more
openalex   +1 more source

Optimization of peptidyl allyl sulfones as clan CA cysteine protease inhibitors [PDF]

, 2012
Brandon D. Fennell, Julia M. Warren, Kevin K. Chung, Hannah L. Main, Andrew B. Arend, A. Tochowicz, Marion G. Götz   +6 more
openalex   +1 more source

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors. [PDF]

Nat Chem Biol
Liu M, Zang X, Vlahakis NW, Rodriguez JA, Ohashi M, Tang Y.   +5 more
europepmc   +1 more source

Cloning of the promoter regions of Trypanosoma brucei and Trypanosoma congolense cysteine protease genes.

, 2013
Thembile Lawrence. Dalasile
openalex   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source