Results 91 to 100 of about 925,943 (256)
BET: Bayesian Ensemble Trees for Clustering and Prediction in Heterogeneous Data [PDF]
arXiv, 2014 We propose a novel "tree-averaging" model that utilizes the ensemble of classification and regression trees (CART). Each constituent tree is estimated with a subset of similar data. We treat this grouping of subsets as Bayesian ensemble trees (BET) and model them as an infinite mixture Dirichlet process.
arxiv
Computation of ancestry scores with mixed families and unrelated individuals [PDF]
arXiv, 2016 The issue of robustness to family relationships in computing genotype ancestry scores such as eigenvector projections has received increased attention in genetic association, as the scores are widely used to control spurious association. We use a motivational example from the North American Cystic Fibrosis (CF) Consortium genetic association study with
arxiv
Rapid method for the detection of cystic fibrosis of the pancreas in children. [PDF]
, 1967 B. A. Saggers +3 more
openalex +1 more source
Physical exercise training for cystic fibrosis.
Cochrane Database of Systematic Reviews, 2017 BACKGROUND Physical exercise training may form an important part of regular care for people with cystic fibrosis. This is an update of a previously published review. OBJECTIVES To assess the effects of physical exercise training on exercise capacity by
T. Radtke +3 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2013 Cystic fibrosis (CF) patients harboring the most common deletion mutation of the cystic fibrosis transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset ...
Valeria Rachela Villella +6 more
doaj +1 more source
Bayesian Model Averaging for the X-Chromosome Inactivation Dilemma in Genetic Association Study [PDF]
arXiv, 2017 X-chromosome is often excluded from the so called `whole-genome' association studies due to its intrinsic difference between males and females. One particular analytical challenge is the unknown status of X-inactivation, where one of the two X-chromosome variants in females may be randomly selected to be silenced.
arxiv
Cystic fibrosis: current therapeutic targets and future approaches
Journal of Translational Medicine, 2017 ObjectivesStudy of currently approved drugs and exploration of future clinical development pipeline therapeutics for cystic fibrosis, and possible limitations in their use.MethodsExtensive literature search using individual and a combination of key words
M. Rafeeq, H. Murad
semanticscholar +1 more source
BMC Pulmonary MedicineBackground Cystic fibrosis (CF) is a genetic multisystem disorder. Inflammatory processes, which presumably begin early in infancy, play a crucial role in the progression of the disease. The detection of inflammatory biomarkers, especially in the airways,
Teresa Fuchs +8 more
doaj +1 more source