Results 81 to 90 of about 5,706,617 (283)

Editorial: Novel Anti-Inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies

Frontiers in Pharmacology, 2021
Carla Maria Pedrosa Ribeiro, Noel Gerard McElvaney, Giulio Cabrini, Giulio Cabrini   +3 more
doaj   +1 more source

Best practices in the treatment of early cystic fibrosis lung disease

Therapeutic Advances in Respiratory Disease, 2017
For many years, management of cystic fibrosis (CF) lung disease was focused on symptomatic treatment of chronic lung infection, which is characterized by cough and sputum production, leading to progressive lung damage. With increasing survival and better
Marijke Proesmans
doaj   +1 more source

Development of lymphangioleiomyomatosis in a female patient with Sjö gren's disease: a review of literature and a case report

Современная ревматология, 2019
Cystic and bullous lung transformation occurs in diseases of various origins: neoplastic, genetically determined, rheumatic, lymphoproliferative, and infectious diseases. The paper presents a review of the literature and a clinical case of a young female
Yu. I. Khvan, S. G. Palshina, V. I. Vasiliev   +2 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]

, 2013
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz, Martin Roderfeld, Roderfeld, Martin, Lisa Hage, Timo Rath (389419), Reinhart Zachoval (76840), Katrin Menendez Menendez (389422), Lutz Naehrlich (389423), Martin Roderfeld (389425), Hage, Lisa, Marion Kügler, Richard Schulz (389424), Marion Kügler (389421), Elke Roeb (389426), Timo Rath, Kügler, Marion, Rath, Timo, Roeb, Elke, Katrin Menendez Menendez, Reinhart Zachoval, Elke Roeb, Menendez Menendez, Katrin, Lutz Naehrlich, Lisa Hage (389420), Zachoval, Reinhart, Naehrlich, Lutz, Schulz, Richard   +26 more
core   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Coexisting cystic lung disease as a rare extra-renal manifestation of autosomal dominant polycystic kidney disease

Radiology Case Reports, 2018
Autosomal dominant polycystic kidney disease (ADPKD) classically presents with multiple bilateral renal cysts and ultimately progresses to end stage renal disease.
Nicole Levy, Partha Hota, Maruti Kumaran
doaj   +1 more source

Lysosome‐Targeted Squaramide Anion Transporters

Chemistry – A European Journal, EarlyView.
Lysosome‐targeted squaramide anion transporters elicit different biological effects depending on the targeting group employed. ABSTRACT Targeting anion transporters to specific organelles has previously been shown to be an effective strategy to enhance their cytotoxicities against cancerous cell lines.
Elba Feo, Edward York, Anthony Thai, William G. Ryder, Daniel A. McNaughton, Philip A. Gale   +5 more
wiley   +1 more source

Blood co-expression modules identify potential modifier genes of diabetes and lung function in cystic fibrosis.

PLoS ONE, 2020
Cystic fibrosis (CF) is a rare genetic disease that affects the respiratory and digestive systems. Lung disease is variable among CF patients and associated with the development of comorbidities and chronic infections.
Fanny Pineau, Davide Caimmi, Milena Magalhães, Enora Fremy, Abdillah Mohamed, Laurent Mely, Sylvie Leroy, Marlène Murris, Mireille Claustres, Raphael Chiron, Albertina De Sario   +10 more
doaj   +1 more source