Results 191 to 200 of about 55,240 (308)

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu   +9 more
wiley   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang   +9 more
wiley   +1 more source

Targeting Myostatin for Sustainable Meat Production: Insights From Multiple Species

open access: yesAnimal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Myostatin gene (MSTN), a TGF‐β superfamily member, negatively regulates skeletal muscle growth, positioning it as a prime genetic target for enhancing livestock meat production. This review synthesizes evidence from 1979 to 2025 on MSTN mutations across cattle, pigs, poultry, sheep, goats, and rabbits, emphasising impacts on yield, quality ...
Chiara Santomassimo   +9 more
wiley   +1 more source

A NEW SYNTHESIS OF CYSTINE

open access: yesJournal of Biological Chemistry, 1948
openaire   +2 more sources

Hematopoietic Stem-Cell Gene Therapy for Cystinosis. [PDF]

open access: yesN Engl J Med
Barshop BA   +19 more
europepmc   +1 more source

Defensin‐DNA Supramolecular Complexes as a New pH‐Sensing Nanomaterial

open access: yesAggregate, Volume 7, Issue 6, June 2026.
Crocodylus porosus β‐defensin 13 (CpoBD13), a host defence peptide from the saltwater crocodile, is discovered to interact with single‐ and double‐stranded DNA to form supramolecular assemblies, termed defensin‐induced spherical complexes (DISCs).
Scott A. Williams   +15 more
wiley   +1 more source

Identification of diagnostic biomarkers for neonatal necrotizing enterocolitis via machine learning screening and single‐cell virtual gene knockout validation

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Integrated machine learning screening of five gene expression omnibus datasets and 113 algorithm combinations identified three candidate diagnostic biomarkers for neonatal necrotizing enterocolitis: SLC26A3 (downregulated), CCL20, and CXCL5 (both upregulated). Single‐cell RNA sequencing localized CCL20 upregulation predominantly to macrophages.
Xue Liu   +5 more
wiley   +1 more source

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