Results 181 to 190 of about 90,075 (287)

N6‐methyladenosine‐RNA methylation promotes expression of solute carrier family 7 member 11, an uptake transporter of cystine for lipid reactive oxygen species scavenger glutathione synthesis, leading to hepatoblastoma ferroptosis resistance

Clinical and Translational Medicine, 2022
Ronald A. Hill, Yong‐Yu Liu
doaj   +1 more source

Aminopeptidase N: the glucocorticoid gateway linking chronic stress to ferroptosis resistance in liver cancer. [PDF]

J Clin Invest
Luo M, Luo W.
europepmc   +1 more source

Xanthatin‐13‐(Pyrrolidine‐2‐Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ25‐35 Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease

Phytotherapy Research, Volume 40, Issue 5, Page 2824-2843, May 2026.
ABSTRACT Alzheimer's disease (AD) is a severe form of dementia, which occurrence increases with age and lifestyle conditions. It is characterized by amyloid protein accumulation forming senile plaques, hyperphosphorylated tau protein forming neurofibrillary tangles, neuroinflammation, and oxidative stress, leading to synapse loss and cell death ...
Charlyne Barry‐Simonnet, Lucie Crouzier, Tristan Moujellil‐Legagneur, Hamza Chaieb‐Errass, Yanis A. Idres, Karine Ferrare, Marc Rolland, Guillaume Cazals, Patrick Poucheret, Tangui Maurice, Didier Tousch   +10 more
wiley   +1 more source

Transsulfuration metabolism is essential for ferroptosis resistance in quiescent endothelial cells. [PDF]

Cell Death Dis
Oberkersch RE, Lidonnici J, Andreuzza S, Zambon E, Imperato G, Pedretti S, Mitro N, Santoro MM.   +7 more
europepmc   +1 more source

A Biomimetic Micro‐Nano System Maximizing ‘Active Transport and Retention’ Effect in Solid Tumors

Small, Volume 22, Issue 25, 4 May 2026.
The Active Transport and Retention (ATR) strategy is realized using a biomimetic micro‐nano system (PG@BAM‐LRC), achieving superior tumor accumulation and efficacy in low‐EPR pancreatic tumors. Platelet (PG)‐derived microcarriers enable tumor‐homing and MMP‐9‐responsive release of nanoliposomes (LRC), while berbamine (BAM) promotes transendothelial ...
Kaiyun Yang, Jiajia Su, Alan J. Davidson, Zimei Wu, Wenli Zhang   +4 more
wiley   +1 more source

Disulfidptosis: A Metabolic Cell Death Mechanism with Therapeutic Potential in Cancer. [PDF]

Oncol Res
Zhao W, Wang Q, Zhang J.
europepmc   +1 more source

Cutibacterium acnes–Derived Extracellular Vesicles Promote Epithelial Ovarian Cancer Progression by Activating the KEAP1–NRF2 Antioxidant Pathway to Suppress Ferroptosis

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
C. acnes‐derived extracellular vesicles promote epithelial ovarian cancer progression. CEVs reprogram redox homeostasis and suppress ferroptosis by modulating key regulators. ABSTRACT Bacterial extracellular vesicles are increasingly recognized as important mediators of microbe–host communication, yet their functional roles within tumour‐associated ...
Qifa Huang, Qi Chen, Wenjie Xiong, Yuexi Sun, Yuxiong Huang, Ang Dai, Jianying Chen, Xue Wu, Ying Jiang, Fen Wei, Qi Chen, Tingtao Chen   +11 more
wiley   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Separate core-shell analysis of urinary stones may influence specific metaphylaxis. [PDF]

World J Urol
Winterhagen FI, Latz S, Jacobs C, Lossin P, Stein J.   +4 more
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source