Exploring the Impact of miR-10a, miR-141, miR-200a and miR-3658 on Cystinuria. [PDF]
Ayres DC +14 more
europepmc +1 more source
Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan +10 more
wiley +1 more source
Cysteine metabolism dysregulation promotes ferroptosis in osteoarthritis: Insights from multi-species bioinformatics and experimental validation. [PDF]
Zheng L +15 more
europepmc +1 more source
Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng +7 more
wiley +1 more source
Advances in ferroptosis mechanisms and therapeutic potential in head and neck squamous cell carcinoma. [PDF]
Tang L, Lin L, Xu C, Guo H.
europepmc +1 more source
Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu +6 more
wiley +1 more source
A targetable FTO/SLC7A11/CBS/CTH axis controls cysteine metabolism, growth and survival in NSCLC. [PDF]
Kuganesan N +10 more
europepmc +1 more source
Quantitative Susceptibility Mapping of Kidney Stones: An Ex Vivo MRI Phantom Study
ABSTRACT Purpose To visualize and characterize the five most common kidney stone types based on their magnetic susceptibilities in MRI using QSM. Methods Three water‐based agar phantoms were constructed, containing a total of 53 ex vivo kidney stones of varying types and sizes.
Lion H. Mücke +8 more
wiley +1 more source
Cystine-Binding Medication Is Poorly Accessible for the Treatment of Cystinuria.
Peng X +11 more
europepmc +1 more source

