Results 141 to 150 of about 47,507 (264)

DKK1 Promotes Cisplatin Resistance in Oral Squamous Cell Carcinoma via SLC3A2‐Dependent Ferroptosis Suppression

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is a prevalent malignancy associated with poor outcomes, largely attributable to cisplatin resistance—the standard chemotherapeutic agent. Aims While ferroptosis has been proposed as a promising therapeutic target, how it is regulated in OSCC remains largely unclear.
Zhuoxuan Liu   +3 more
wiley   +1 more source

Obesity Increases Atherosclerosis Susceptibility via an Intertissue miR-30e-SLC7A11 Axis. [PDF]

open access: yesCirc Res
Wang C   +23 more
europepmc   +1 more source

Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu   +6 more
wiley   +1 more source

Hepatoprotective Effects of Maillard Reaction Products From Perinereis aibuhitensis: Identification and Metabolomic Insights in a Mouse Model of Alcoholic Liver Disease

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract summarizes the hepatoprotective effects of Maillard reaction products derived from Perinereis aibuhitensis (P‐MRPs) in alcohol‐induced liver injury. Male ICR mice were fed a Lieber‐DeCarli alcohol liquid diet (1%–5%, w/v) for 6 weeks with or without P‐MRPs treatment.
Tonglei Qiao   +5 more
wiley   +1 more source

Amino acid profiles and clinical phenotypes in young children with autism spectrum disorder. [PDF]

open access: yesFront Neurosci
Serati I   +23 more
europepmc   +1 more source

Chemical Composition and In Vitro Bioactive Potential of Dried Honeybee (Apis mellifera L.) Podmore as a Candidate Functional Food Ingredient

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Dried honeybee podmore was evaluated as a sustainable functional food ingredient. The extract showed high protein, lipids, balanced amino acids, chitin, chitosan, minerals, phenolics, and flavonoids. It exhibited antioxidant activity, inhibited pancreatic lipase and alpha glucosidase, and enhanced insulin secretion in MIN6 beta cells, supporting ...
Marwa Rashad Ali   +4 more
wiley   +1 more source

Antimicrobial Susceptibility Patterns and Proportion of Multidrug‐Resistant Uropathogens in a Remote Tertiary Hospital in Bhutan: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims A surge in antimicrobial resistance and multidrug‐resistant organisms among uropathogens have complicated its management over time. It is imperative to examine epidemiology and local antimicrobial susceptibility patterns to promote evidence‐based management.
Sanga Tenzin   +7 more
wiley   +1 more source

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