Results 121 to 130 of about 55,240 (308)
Differences between OK and LLC-PK1 cells: cystine handling
, 1991 Cultured opossum kidney (OK) and porcine kidney (LLC-PK1) cells were compared for biochemical characteristics and cystine transport systems. The cell lines differ in amount of protein per cell, with OK cells having approximately one-half the amount found
B. States, S. Segal, D. Harris
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Macronutrient and micronutrient profiles of meat types: insights into human health and diet
Journal of the Science of Food and Agriculture, EarlyView.Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş +4 more
wiley +1 more source
The effect of environment on cystine disruption by ultraviolet light
, 1967 When cystine is irradiated at pH 1 by 254-nm u.v. the following yields are observed: 4 cystines → 5.2 cysteines + 2.8NH3. Thus, SH production accounts for only 0.65 of the cystine destruction; further C-S breakage to give alanine or serine is not ...
Dose, K. +3 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu +8 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao +6 more
wiley +1 more source
Formation of cystine slipknots in dimeric proteins.
, 2013 We consider mechanical stability of dimeric and monomeric proteins with the cystine knot motif. A structure based dynamical model is used to demonstrate that all dimeric and some monomeric proteins of this kind should have considerable resistance to ...
Mateusz Sikora (257612) +5 more
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Molecular Carcinogenesis, EarlyView.ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang +4 more
wiley +1 more source
Cystine reductase in the dimorphic fungus Histoplasma capsulatum
, 1978 Organo-sulfur compounds favor the transition of mycelia of Histoplasma capsulatum to the yeast form (6, 8). Investigation of the role of cystine in the transition revealed that the two phases concentrated this amino acid at comparable rates and that ...
MARESCA, Bruno +3 more
core
The RON2 cystine loop governs specificity.
, 2012 (A). Alignment of RON2 sequences truncated to correlate PfRON2sp1 with RON2 sequences from the following accession numbers: TgRON2 - TGME49_100100, NcRON2 - NCLIV_064620, PfRON2 - PF14_0495, PvRON2 - PVX_117880, PyRON2 – PY_06813, BbRON2 (BBOV_I001630). (
Graham A. Bentley (152106) +10 more
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Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source