Results 281 to 290 of about 112,393 (379)

The NF-κB-SLC7A11 axis regulates ferroptosis sensitivity in inflammatory macrophages. [PDF]

open access: yesCell Insight
Yang M   +9 more
europepmc   +1 more source

Programmed Cell Death in Cancer

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Cancer is one of the most common and lethal diseases globally, with programmed cell death (PCD) playing a pivotal role in its pathogenesis and treatment. This comprehensive review covers the origin, developmental trajectory, and mechanisms of various PCDs, as well as their molecular connections with cancers. Latest studies have increasingly highlighted
Yuang Wei   +3 more
wiley   +1 more source

Plant cystine-knot peptides: pharmacological perspectives.

open access: yesBritish Journal of Clinical Pharmacology, 2017
B. Molesini   +4 more
semanticscholar   +1 more source

Dehydrocostus Lactone Effectively Alleviates Inflammatory Diseases by Covalently and Irreversibly Targeting NLRP3

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Dehydrocostus lactone (DCL) covalently binds to NLRP3 and effectively reduces the interaction between NEK7 and NLRP3, thereby blocking the assembly of NLRP3 inflammasome complex and subsequent activation in macrophages. Consequently, DCL inhibits the cleavage and maturation of pro‐IL‐1β and pro‐IL‐18, ultimately leading to the suppression of the ...
Qi Lv   +14 more
wiley   +1 more source

Neurotransmitter signaling in white matter [PDF]

open access: yes, 2014
Butt, Arthur M.   +2 more
core   +1 more source

Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas.

open access: yesCancer Research, 2016
Xiaohu Tang   +10 more
semanticscholar   +1 more source

Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Glutamine deprivation can promote PUFA oxidation and PTGS2 expression through the upregulation of intracellular ROS, but not ferroptosis. Because glutamine deficiency exhausts mitochondrial ATP, thereby hinders the conversion of PUFA into their active form of PUFA‐CoA needed for lipid synthesis.
Chaoyi Xia   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy