Results 311 to 320 of about 112,393 (379)
Exploring the role of ferroptosis in esophageal cancer: mechanisms and therapeutic implications. [PDF]
Zhao D, Li W, Han Z, Wang Z, Li D, Li W.
europepmc +1 more source
THE CONVERSION OF S35-HOMOLANTHIONINE TO S35-CYSTINE IN THE RAT
Jakob A. Stekol, Kathryn. Weiss
openalex +1 more source
Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin+13 more
wiley +1 more source
Targeting Ferroptosis: Emerging Insights into Osteoporosis Mechanisms. [PDF]
Yang H+5 more
europepmc +1 more source
ABSTRACT Haematological malignancies encompass a wide spectrum of blood cell disorders with diverse prognoses. Despite recent advances in therapy, many of these disorders remain incurable or exhibit relapse and drug resistance. Ferroptosis, an iron‐dependent form of cell death caused by lipid peroxidation, holds promise as a strategy to overcome the ...
Maryam Shayanmanesh+2 more
wiley +1 more source
Selective oxidative modification of tryptophan and cysteine residues using visible light responsive Rh doped SrTiO<sub>3</sub> photocatalyst. [PDF]
Usuki S+6 more
europepmc +1 more source
Natural Agents Modulating Ferroptosis in Cancer: Molecular Pathways and Therapeutic Perspectives
ABSTRACT Ferroptosis, a controlled cell death influenced by iron‐dependent lipid peroxidation, presents potential therapeutic targets for cancer treatment due to its unique molecular pathways and potential drug resistance. Natural compounds, such as polyphenols, flavonoids, terpenoids and alkaloids, can influence ferroptosis via important signalling ...
Md. Al Amin+12 more
wiley +1 more source
Amide Chemistry Enables Redox Locking of Cyclic Disulfides for Polypeptide Assembly
The stability of a family of cyclic dichalcogenides derived from cysteine is significantly enhanced against reductants upon acylation of the alpha‐amino group. Amide formation serves as a redox lock, offering a mechanism to achieve selectivity in the assembly of large cyclic polypeptides on a water‐compatible solid support.
Vincent Diemer+4 more
wiley +2 more sources