Results 61 to 70 of about 7,801 (251)

Transplantation in children [PDF]

, 1976
Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam, DeShazo, Kendrick A. Porter, Lilly, Lilly, Richard Weil, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Thomas E. Starzl   +15 more
core   +1 more source

Revealing VNN1: An Emerging and Promising Target for Inflammation and Redox Balance

Immunity, Inflammation and Disease, Volume 13, Issue 10, October 2025.
ABSTRACT Introduction The intricate balance between immunometabolic homeostasis and redox equilibrium is crucial for maintaining health, and its dysregulation is implicated in a wide spectrum of diseases. Vascular non‐inflammatory molecule‐1 (VNN1) is an emerging pantetheinase that sits at the crossroads of inflammation and metabolism, yet a ...
Linxi Lv, Tian Wang, Wenzhan Xie, Jialong Wei, Laixian Zhou, Xiaopei Qiu, Hui Feng, Wei Gu   +7 more
wiley   +1 more source

Cognitive functions and behavioural profiles in children with cystinosis treated with cysteamine and correlation with treatment duration

Middle East Current Psychiatry, 2022
Background Cystinosis is a rare autosomal recessive disease. Children with nephropathic cystinosis (NCTN) have evidence of intellectual dysfunction and behavioural abnormalities which are attributed to renal dysfunction, metabolic disarrangement, and ...
Fatma M. Atia, Weam Ryad Alfaleet, Somaya H. Shaheen, Neveen A. Soliman   +3 more
doaj   +1 more source

In Vitro and In Vivo Models to Study Nephropathic Cystinosis

Cells, 2021
The development over the past 50 years of a variety of cell lines and animal models has provided valuable tools to understand the pathophysiology of nephropathic cystinosis. Primary cultures from patient biopsies have been instrumental in determining the
Pang Yuk Cheung, Patrick T. Harrison, Alan J. Davidson, Jennifer A. Hollywood   +3 more
doaj   +1 more source

Dialysis Vintage and Symptom Burden in Hemodialysis: A Comprehensive Analysis

Nursing &Health Sciences, Volume 27, Issue 3, September 2025.
ABSTRACT End‐stage renal disease (ESRD) requires lifelong maintenance hemodialysis (MHD), and patients commonly experience a high symptom burden that affects their quality of life. This study explores the impact of dialysis vintage on symptom burden and quality of life in ESRD patients undergoing MHD.
Shanshan Yan, Ya Wang, Zhenzhen Li, Duo Wang, Dongfang Yao   +4 more
wiley   +1 more source

Nephropathic Cystinosis : First reported case in Oman

Sultan Qaboos University Medical Journal, 2011
Cystinosis is an autosomal recessive, lysosomal storage disease characterised by the accumulation of the amino acid cystine in different organs and tissues. It is a multisystemic disease that can present with renal and extra renal manifestations.
Dana Al-Nabhani, Mohammed El-Naggari, Rana Al-Sinawi, Alexander P. Chacko, Anuradha Ganesh, Ibtisam El Nour   +5 more
doaj  

Glutathione depletion and increased apoptosis rate in human cystinotic proximal tubular cells [PDF]

, 2018
We have determined levels of glutathione (GSH), ATP, mitochondrial complex activity and apoptosis rate in proximal tubular cells (PTCs) exfoliated from urine in cystinotic (n=9) and control (n=9) children.
Haq, Mushfequr, Hargreaves, Iain, Heales, Simon, Laube, Guido, Shah, Vanita, Stewart, Victoria, van't Hoff, William   +6 more
core  

Executive Functioning and Mental Health in Adolescent Kidney Transplant Candidates During the COVID‐19 Pandemic

Pediatric Transplantation, Volume 29, Issue 6, September 2025.
Adolescent kidney transplant candidates, not preadolescent candidates, exhibited greater executive functioning difficulties and mental health concerns during the COVID‐19 pandemic compared to adolescent candidates evaluated before the pandemic.
Finola E. Kane‐Grade, Danielle Glad, Christopher Anzalone, Michael D. Evans, Sarah Kizilbash, Lidan Gu   +5 more
wiley   +1 more source

Unveiling cystinosis in India

Journal of Rare Diseases
Background Cystinosis, a rare autosomal recessive disease, stems from genetic alterations in the CTNS gene, leading to a malfunction of lysosomal ‘cystinosin’ protein.
Aniruddh Heroor, Anshuman Verma, Divya Sree Achanta, Deepak Paul Edward, Muralidhar Ramappa   +4 more
doaj   +1 more source

Fertility Management in Cystinosis: A Clinical Perspective

Kidney International Reports
Cystinosis is a rare, inherited, lysosomal storage disorder characterized by the progressive accumulation of intralysosomal cystine and subsequent organ and tissue damage. The kidneys are the first and most severely impacted organ.
Craig B. Langman, Rowena B. Delos Santos, Cybele Ghossein, Andrea M. Atherton, Elena N. Levtchenko, Aude Servais   +5 more
doaj   +1 more source