Results 121 to 130 of about 87,437 (368)

Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]

open access: yes, 2010
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Höltje, H.-D.   +3 more
core   +1 more source

Mutation profiling in differential diagnosis between TdT‐positive high‐grade/large B‐cell lymphoma and B‐lymphoblastic leukaemia/lymphoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Terminal deoxynucleotidyl transferase (TdT) is occasionally expressed in large B‐cell lymphoma (LBCL), and this causes difficulty in differential diagnosis from B‐lymphoblastic leukaemia/lymphoma (B‐ALL/LBL). We reviewed 31 cases of TdT‐positive LBCL and B‐ALL/LBL, and their final diagnosis included 19 diffuse large/high‐grade BCLs with MYC ...
Maria‐Myrsini Tzioni   +27 more
wiley   +1 more source

Rational design of a new cytarabine-based prodrug for highly efficient oral delivery of cytarabine

open access: yesRSC Advances, 2018
To overcome the drawbacks of cytarabine such as bad liposolubility and low bioavailability, we rationally designed a new cytarabine-based prodrug for oral cytarabine delivery, realizing significantly enhanced bioavailability for cancer therapy.
Jing Zhang   +5 more
openaire   +3 more sources

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes   +2 more
wiley   +1 more source

Enasidenib in the treatment of relapsed/refractory acute myeloid leukemia: an evidence-based review of its place in therapy. [PDF]

open access: yes, 2019
Introduction: Acute myeloid leukemia (AML) remains a disease with high mortality, especially for older patients and those with relapsed/refractory (R/R) disease.
Galkin, Maria, Jonas, Brian A
core   +1 more source

Therapy reduction in patients with Down syndrome and myeloid leukemia: the international ML-DS 2006 trial [PDF]

open access: yes, 2017
Children with myeloid leukemia associated with Down syndrome (ML-DS) have superior outcome compared with non-DS patients, but suffer from higher constitutional cytotoxic drug susceptibility.
Creutzig, U.   +10 more
core   +4 more sources

Time to progression of mantle cell lymphoma after high‐dose cytarabine‐based regimens defines patients risk for death

open access: yesBritish Journal of Haematology, 2018
The current standard treatment of younger patients with mantle cell lymphoma (MCL) includes rituximab and highdose cytarabine (HD-AraC), usually followed by autologous stem cell transplantation (ASCT).
C. Visco   +34 more
semanticscholar   +1 more source

A critical review of management of allogeneic transplant‐eligible adults with Ph+ acute lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
wiley   +1 more source

Recent Advances in Treatment of Primary Central Nervous System Lymphoma [PDF]

open access: yes, 2014
Opinion statement Therapeutic options are limited in primary central nervous system lymphoma (PCNSL) with no uniform consensus on optimal management and few published, randomized trials.
Batchelor, Tracy T., Nayak, Lakshmi
core   +1 more source

Delivery of cytarabine by pegylated liposomes for efficient, long-term anticancer effects [PDF]

open access: yes, 2014
The cytosine arabinoside cytarabine is an effective marine-derived antineoplastic agent for the treatment of acute myelogrnous and lymphocytic leukemias.
Borges, C.   +7 more
core  

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