The evaluation of low-dose cytarabine in the treatment of myelodysplastic syndromes: a phase-III intergroup study [PDF]
K B Miller+8 more
openalex +1 more source
ABSTRACT Adults with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL) have poorer outcomes than pediatric patients. The aim of this systematic literature review and meta‐analysis was to compare asparaginase (ASP)‐containing pediatric‐inspired regimens (PIRs) with hyper‐fractionated cyclophosphamide, vincristine, doxorubicin, and ...
Wenqing Su+5 more
wiley +1 more source
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia [PDF]
Gary J. Schiller+6 more
openalex +1 more source
Acute Myeloid Leukemia: 2025 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Disease Overview Acute myeloid leukemia (AML) is a bone marrow stem cell cancer that is often fatal despite available treatments. Diagnosis, risk assessment, monitoring, and therapeutic management of AML have changed dramatically in the last decade due to increased pathophysiologic understanding, improved assessment technology, and the ...
Shai Shimony+2 more
wiley +1 more source
The role of systemic high-dose cytarabine in the treatment of central nervous system leukemia clinical results in 46 patients [PDF]
Enrica Morra+9 more
openalex +1 more source
ABSTRACT Immunochemotherapy has demonstrated high cure rates in primary mediastinal large B‐cell lymphoma (PMBCL). Recent findings from the IELSG 37 study show that certain specific dose‐dense treatment regimens are more likely to eliminate the need for consolidative radiation therapy, thereby reducing long‐term toxicity. Here, we report our experience
Robin Noel+16 more
wiley +1 more source
Detection of cytarabine resistance in patients with acute myelogenous leukemia using flow cytometry [PDF]
Francis Lacombe+8 more
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Multi‐Omic Evaluation of PLK1 Inhibitor—Onvansertib—In Colorectal Cancer Spheroids
ABSTRACT Polo‐like kinase 1 (Plk1) is a serine/threonine kinase involved in regulating the cell cycle. It is activated by aurora kinase B along with the cofactors Borealin, INCE, and survivin. Plk1 is involved in the development of resistances to chemotherapeutics such as doxorubicin, Taxol, and gemcitabine.
Brian D. Fries+3 more
wiley +1 more source
Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia [PDF]
Wiernik Ph+8 more
openalex +1 more source
International Journal of Laboratory Hematology, EarlyView.
Katie Liston, Vitaliy Mykytiv
wiley +1 more source