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Cytidine and deoxycytidylate deaminase inhibition by uridine analogs
Biochemical Pharmacology, 1980Cytidine deaminase, an enzyme found in the supernatant fluid of hepatocytes, granulocytes and tumor cells, and in plasma, degrades the antitumor agents cytosine arabinoside and 5-azacytidine. Uridine and its analogs, 3-deazauridine, 5-bromodeoxyuridine, 5-fluorodeoxyuridine and 6-azauridine, were found to competitively inhibit cytidine deaminase; the ...
J C, Drake +3 more
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Multifaceted antiviral actions of APOBEC3 cytidine deaminases
Trends in Immunology, 2006To defend against external pathogens, metazoan organisms have evolved numerous defenses that generally fall within the innate and adaptive immune responses. Considerable effort continues to focus on developing a vaccine to manipulate the adaptive immune system to protect against or control HIV-1.
Ya-Lin, Chiu, Warner C, Greene
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The cytidine deaminase family: a review
2009in ...
VINCENZETTI, Silvia +2 more
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Role of cytidine deaminase in toxicity and efficacy of nucleosidic analogs
Expert Opinion on Drug Metabolism and Toxicology, 2015Joseph Ciccolini +2 more
exaly
Molecular characterization of activation-induced cytidine deaminase
Molecular Immunology, 2010Jean-Pol Frippiat
exaly
Serum cytidine deaminase assay—some pitfalls
BJOG: An International Journal of Obstetrics & Gynaecology, 1986D D, Jones, E L, Roberts, G F, Williams
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