Results 101 to 110 of about 12,489 (172)

A Rapid Approach for Identifying Cell Lines Lacking Functional Cytidine Deaminase

CDD plays a pivotal role within the pyrimidine salvage pathway. In this study, a novel, rapid method for the identification of cell lines lacking functional cytidine deaminase was developed. This innovative method utilizes immunocytochemical detection of
Anna Ligasová, Markéta Kociánová, Karel Koberna   +2 more
core   +1 more source

Regulation of colominic acid biosynthesis by temperature: Role of cytidine 5′-monophosphate N-acetylneuraminic acid synthetase

, 1989
Synthesis of colominic acid in Escherichia coli K-235 is strictly regulated by temperature. Evidence for the role of cytidine 5′-monophospho-N-acetylneuraminic acid (CMP-Neu5Ac) synthetase in this regulation was obtained by measuring its level in E. coli
González-Clemente, Camino, Leandro B. Rodríguez-Aparicio, José M. Luengo, Reglero, Angel, Angel Reglero, Luengo, José M., Rodríguez-Aparicio, Leandro B., Camino González-Clemente   +7 more
core   +1 more source

Lowback Pain Management with a Combination of Uridine Triphosphate, Cytidine Monophosphate, and Hydroxocobalamin: A Systematic Review and Meta-Analysis. [PDF]

Rev Bras Ortop (Sao Paulo)
Mibielli MAN, Suchmacher M, Geller M, Mezitis SGE, Nunes CP, Sintoveter A.   +5 more
europepmc   +2 more sources

Generation and characterization of genetically modified pigs with GGTA1/β4GalNT2/CMAH knockout and human CD55/CD47 expression for xenotransfusion studies

Scientific Reports
Pig red blood cells (pRBCs) represent a promising alternative to address the shortage in transfusion medicine. Nonetheless, a major obstacle to their clinical implementation is immunological rejection.
Bin Fang, Chunting Wang, Yilin Yuan, Xiaorui Liu, Lili Shi, Lin Li, Ying Wang, Yifan Dai, Haiyuan Yang   +8 more
doaj   +1 more source

Cytidine 3':5'-monophosphate phosphodiesterase in mammalian tissues. Occurrence and biological involvement

, 1978
A phosphodiesterase activity that preferentially hydrolyzed cytidine 3':5'-monophosphate was partially purified from rat liver extract. The enzyme was best activated by Fe2+ (5 to 10 mM).
Kuo, J F, Brackett, N L, Shoji, M, Tse, J   +3 more
core  

CMPK2 promotes NLRP3 inflammasome activation via mtDNA‐STING pathway in house dust mite‐induced allergic rhinitis

Clinical and Translational Medicine
Background House dust mite (HDM) is the leading allergen for allergic rhinitis (AR). Although allergic sensitisation by inhaled allergens renders susceptible individuals prone to developing AR, the molecular mechanisms driving this process remain ...
YaoMing Zheng, YaDong Xie, JiaYing Li, YuJie Cao, Min Li, Qing Cao, MiaoMiao Han, HongFei Lou, YiLai Shu, Hui Xiao, HuaBin Li   +10 more
doaj   +1 more source

The influence of APOBEC3G and deoxythymidylate kinase genetic diversity on HIV-1 hypermutation and response to treatment

, 2006
This thesis addresses two important topics in HIV-1 medicine; (i) the clinical relevance of pre-treatment G-A hypermutation and the contribution of host and viral genetics to its development and; (ii) the influence of genetic variation in host enzymes ...
Pace, Craig Stuart
core  

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells. [PDF]

Onco Targets Ther, 2018
O'Day EM, Idos GE, Hill C, Chen JW, Wagner G.   +4 more
europepmc   +1 more source

A reversed phase HPLC method for the analysis of nucleotides to determine 5’-PDE enzyme activity

Bulletin of the Chemical Society of Ethiopia, 2010
5’-Phosphodiesterase (5'-PDE) can be extracted from barley roots and used as a catalyst in the hydrolysis of RNA to produce 5'-nucleotides. The assay of enzyme activity is essential for the production of 5'-PDE.
Jie Hua, Ke-long Huang
doaj  

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

iMeta
Curcuminoids, including curcumin (CUR) and demethoxycurcumin (DMC), are known for their antiviral properties, but their underlying antiviral targets remain unclear, and the relationship between curcuminoids and the type I interferon (IFN‐I) signaling ...
Tingting Chen, Xiang Wang, Guangyuan Zhang, Lu Wang, Junhao Wan, Lirong Tan, Xinyue Fan, Siqin Meng, Zhixing Jin, Yuzhang Liang, Haoze Li, Ziyuan Wan, Xiaotong Xu, Yan Zhang, Li Qin, Anna Malashicheva, Yu Du, Guangchao Zang, Guixue Wang   +18 more
doaj   +1 more source