Results 81 to 90 of about 12,489 (172)

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Gene Editing Technique in Xenotransplantation

Frontiers in Immunology, 2018
Genetically modified pigs have been considered favorable resources in xenotransplantation. Microinjection of randomly integrating transgenes into zygotes, somatic cell nuclear transfer, homologous recombination, zinc finger nucleases, transcription ...
Meisam Naeimi Kararoudi, Seyyed S. Hejazi, Ezgi Elmas, Mats Hellström, Maryam Naeimi Kararoudi, Arvind M. Padma, Dean Lee, Hamid Dolatshad   +7 more
doaj   +1 more source

Mitochondrial‐Haplotype Influences Plasma Metabolome, Lipidome, and Proteome in a Sex Specific Manner in the Genetically Heterogenous OKC‐HETB/W Rat

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Multi‐omics profiling uncovers the effect of sex and mitochondrial‐haplotype on molecular fingerprints of aging in plasma. ABSTRACT The effect of mitochondrial‐haplotype (mt‐haplotype) on aging was studied using a unique rat model (OKC‐HETB/W), which has a heterogenous nuclear background combined with mitochondria from either Brown Norway (B‐haplotype)
Hoang Van M. Nguyen, Finterly Hu, Evaniya Shakya, Chloe Fender, Kenneth Lee, Jason Schindler, Manuel Garcia‐Jaramillo, Nagib Ahsan, Janet C. Siebert, Sarah J. Borengasser, Norman G. Hord, Michael B. Stout, Steven Austad, Arlan Richardson   +13 more
wiley   +1 more source

PROTON AND PHOSPHORUS NMR STUDY ON THE BINDING OF CYTIDINE MONOPHOSPHATE INHIBITORS TO RIBONUCLEASE A.

, 1975
PROTON AND PHOSPHORUS NMR STUDY ON THE BINDING OF CYTIDINE MONOPHOSPHATE INHIBITORS TO RIBONUCLEASE ...
ALICE MARY. WYRWICZ (7971686)
core  

Quality Formation Mechanism during the Developmental Process of Morchella Fruiting Bodies Based on Metabolomic Analysis [PDF]

Shipin Kexue
This study investigated the dynamic changes of quality formation and metabolite profiles during the development of Morchella fruiting bodies. Morchella fruiting bodies at three developmental stages: primordium (YJ), small mushroom (XG), and mature ...
LI Yunfan, LI Yuxin, REN Haiwei, XIANG Yumeng, GUO Xiaopeng, SHI Renjie, LIU Qiankui, WANG Yayu
doaj   +1 more source

Intramolecular Proton Transfer in the Radical Anion of Cytidine Monophosphate Sheds Light on the Sensitivities of Dry vs Wet DNA to Electron Attachment-Induced Damage. [PDF]

J Am Chem Soc, 2023
Chomicz-Mańka L, Czaja A, Falkiewicz K, Zdrowowicz M, Biernacki K, Demkowicz S, Izadi F, Arthur-Baidoo E, Denifl S, Zhu Z, Tufekci BA, Harris R, Bowen KH, Rak J.   +13 more
europepmc   +1 more source

Chemoenzymatic Synthesis and Enzymatic Analysis of 8-Modified Cytidine Monophosphate-Sialic Acid and Sialyl Lactose Derivatives

, 2016
The sialic acids found on eukaryotic glycans have remarkably diverse core structures, with a range of modifications at C5, C7, C8 and C9. These carbohydrates have been found to play key roles in cell−cell interactions within eukaryotes and often serve as
Thomas J. Morley (2285419), Stephen G. Withers (1316403)   +1 more
core   +1 more source

Unveiling the pathways of flavor formation in marinated lamb driven by ultrasound-assisted vacuum tumbling: An integrated multi-omics approach

Ultrasonics Sonochemistry
The development of desirable flavor in processed lamb remains a significant challenge for the meat industry. This study aimed to investigate the effects of ultrasound-assisted vacuum tumbling (UVT) on the flavor characteristics of lamb using a combined ...
Chenchen Xu, Shouwei Wang, Yan Zhao, Jiapeng Li, Shunliang Zhang, Jing Bai, Yuxuan Shi, Xianqi Yao, Anyu Gao, Bing Zhao   +9 more
doaj   +1 more source

MOESM3 of Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity

, 2019
Additional file 3. Scheme depicting the role of dUTPase in pyrimidine metabolism. UMP/CMPK (putative), uridine monophosphate/cytidine monophosphate kinase; NDK, nucleoside-diphosphate kinase; CTPS, cytidine triphosphate synthetase; RNR, ribonucleotide ...
Shahienaz Hampton (8079062), Ian Gilbert (4578127), Sylke Müller (37476), Guiomar Pérez-Moreno (843822), Luis Ruiz-Pérez (8079056), Nils Johansson (8079059), Sandipan Sarkar (2229988), Marcel Kaiser (41510), Vijeesh Kumar (8079068), Dolores González-Pacanowska (501255), Beatriz Baragaña (3040353), Paula Sánchez-Carrasco (843823), Thiyagamurthy Pandurangan (8079065)   +12 more
core   +1 more source

Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system

Nature Communications
3’,5’-cyclic uridine monophosphate (cUMP) and 3’,5’-cyclic cytidine monophosphate (cCMP) have been established as bacterial second messengers in the phage defense system, named pyrimidine cyclase system for anti-phage resistance (Pycsar).
Mei-Hui Hou, Chao-Jung Chen, Chia-Shin Yang, Yu-Chuan Wang, Yeh Chen   +4 more
doaj   +1 more source

Cardiovascular effects of CDP-choline and its metabolites: Involvement of peripheral autonomic nervous system

, 2007
Intraperitoneal administration of CDP-choline (200-900 mu mol/kg) increased blood pressure and decreased heart rate of rats in a dose- and time-dependent manner.

core   +1 more source