Results 81 to 90 of about 11,913 (180)

Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase and Solute Carrier Family 35 Member A1 Are Required for Reovirus Binding and Infection. [PDF]

J Virol, 2020
Urbanek K, Sutherland DM, Orchard RC, Wilen CB, Knowlton JJ, Aravamudhan P, Taylor GM, Virgin HW, Dermody TS.   +8 more
europepmc   +1 more source

Pigment epithelium‑derived factor facilitates NLRP3 inflammasome activation through downregulating cytidine monophosphate kinase 2: A potential treatment strategy for missed abortion. [PDF]

Int J Mol Med, 2020
Zhang X, Zhang K, Zhang Y.
europepmc   +1 more source

Use of nucleotides in weanling rats with diarrhea induced by a lactose overload: effect on the evolution of diarrhea and weight and on the histopathology of intestine, liver and spleen

Brazilian Journal of Medical and Biological Research, 2001
Until recently, dietary sources of nucleotides were thought not to be essential for good nutrition. Certain states with higher metabolic demands may require larger amounts that cannot be provided by endogenous production.
Norton R., Leite J., Vieira E., Bambirra E., Moura C., Penna G., Penna F.   +6 more
doaj  

Exploring the Mutated Kinases for Chemoenzymatic Synthesis of N4-Modified Cytidine Monophosphates

Molecules
Nucleosides, nucleotides, and their analogues are an important class of molecules that are used as substrates in research of enzymes and nucleic acid, or as antiviral and antineoplastic agents. Nucleoside phosphorylation is usually achieved with chemical methods; however, enzymatic phosphorylation is a viable alternative.
Martyna Koplūnaitė, Kamilė Butkutė, Jonita Stankevičiūtė, Rolandas Meškys   +3 more
openaire   +3 more sources

Lowback Pain Management with a Combination of Uridine Triphosphate, Cytidine Monophosphate, and Hydroxocobalamin: A Systematic Review and Meta-Analysis. [PDF]

Rev Bras Ortop (Sao Paulo)
Mibielli MAN, Suchmacher M, Geller M, Mezitis SGE, Nunes CP, Sintoveter A.   +5 more
europepmc   +2 more sources

Generation and characterization of genetically modified pigs with GGTA1/β4GalNT2/CMAH knockout and human CD55/CD47 expression for xenotransfusion studies

Scientific Reports
Pig red blood cells (pRBCs) represent a promising alternative to address the shortage in transfusion medicine. Nonetheless, a major obstacle to their clinical implementation is immunological rejection.
Bin Fang, Chunting Wang, Yilin Yuan, Xiaorui Liu, Lili Shi, Lin Li, Ying Wang, Yifan Dai, Haiyuan Yang   +8 more
doaj   +1 more source

Advances in human glutamine-hydrolyzing synthetases and their therapeutic potential

Frontiers in Chemical Biology
Bifunctional enzymes, characterized by their dual active sites, enable efficient chemical conversion and substrate channeling using elegant coupling mechanisms to coordinate the two active sites. In humans, several bifunctional enzymes synthesize de novo
Wen Zhu, Alanya J. Nardone, Lucciano A. Pearce   +2 more
doaj   +1 more source

CMPK2 promotes NLRP3 inflammasome activation via mtDNA‐STING pathway in house dust mite‐induced allergic rhinitis

Clinical and Translational Medicine
Background House dust mite (HDM) is the leading allergen for allergic rhinitis (AR). Although allergic sensitisation by inhaled allergens renders susceptible individuals prone to developing AR, the molecular mechanisms driving this process remain ...
YaoMing Zheng, YaDong Xie, JiaYing Li, YuJie Cao, Min Li, Qing Cao, MiaoMiao Han, HongFei Lou, YiLai Shu, Hui Xiao, HuaBin Li   +10 more
doaj   +1 more source

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells. [PDF]

Onco Targets Ther, 2018
O'Day EM, Idos GE, Hill C, Chen JW, Wagner G.   +4 more
europepmc   +1 more source

A reversed phase HPLC method for the analysis of nucleotides to determine 5’-PDE enzyme activity

Bulletin of the Chemical Society of Ethiopia, 2010
5’-Phosphodiesterase (5'-PDE) can be extracted from barley roots and used as a catalyst in the hydrolysis of RNA to produce 5'-nucleotides. The assay of enzyme activity is essential for the production of 5'-PDE.
Jie Hua, Ke-long Huang
doaj