Results 171 to 180 of about 6,252 (195)

Plasmodium falciparum cytoadherence

Research in Immunology, 1991
Sherman, I.W. (1979), Biochemistry of Plasmodium (malaria parasites). Microbiol. Rev., 43, 453-495. Strych, W., Miettinen-Baumann, A., Lottspeich, F. & Heidrich, H. (1987), Isolation and characterisation of the 80,000 dalton Plasmodium falciparum merozoite surface antigen. Parasit. Res., 73, 435441. Stryer, L.
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Plasmodium falciparum: Cytoadherence of a knobless clone

Experimental Parasitology, 1989
Sequestration of Plasmodium falciparum-infected erythrocytes is crucial to parasite survival as it prevents destruction in the liver and spleen. Knobs have been considered necessary but not sufficient for cytoadherence to vascular endothelial cells in vivo and to melanoma or umbilical vein endothelial cells in vitro.
BIGGS, BA, CULVENOR, JG, NG, JS, KEMP, DJ, BROWN, GV   +4 more
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Host response to cytoadherence inPlasmodium falciparum

Biochemical Society Transactions, 2008
Cytoadherence of PRBCs (Plasmodium falciparum-infected red blood cells) to host endothelium has been associated with pathology in severe malaria, but, despite extensive information on the primary processes involved in the adhesive interactions, the mechanisms underlying the disease are poorly understood.
Srabasti J, Chakravorty, Katie R, Hughes, Alister G, Craig   +2 more
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Sticky rings: challenging the cytoadherence dogma

Trends in Parasitology, 2001
The accumulation of red blood cells (RBCs) parasitized by Plasmodium falciparum in many organs, particularly the brain and placenta, is probably the most extensively studied phenomenon in the pathogenesis of falciparum malaria. Parasitized RBCs (PRBCs) sequester as a result of receptor–ligand interactions between surface molecules on PRBCs and vascular
Brian M Cooke, James G Beeson, Stephen J Rogerson   +2 more
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Spleen modulation of cytoadherence properties of Plasmodium falciparum

Scandinavian Journal of Infectious Diseases, 2009
Cytoadherence to CD36 and ICAM-1 and var gene expression of P. falciparum parasites from a splenectomized patient were studied. These parasites lacked cytoadherence and showed expression of a non-coding cDNA sequence. Hence the spleen's modulation of parasite cytoadherence by mechanisms that affect the parasite's surface antigen expression is suggested.
Anjanie, Munasinghe, Manjula, Ileperuma, Gayani, Premawansa, Shiroma, Handunnetti, Sunil, Premawansa   +4 more
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CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes

Cell, 1989
Erythrocytes infected with P. falciparum express knob-like adhesion structures that allow the infected cells to cling to the postcapilliary endothelium of characteristic host organs. At present, the mechanism of cytoadherence is not fully understood.
P, Oquendo, E, Hundt, J, Lawler, B, Seed
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Cerebral Malaria in Children: Clinical Implications of Cytoadherence

The American Journal of Tropical Medicine and Hygiene, 1990
In endemic areas, most of the people who die from falciparum malaria are young children. Death is commonly preceded by coma (cerebral malaria). The possible role of cytoadherence in this clinical picture is considered.
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Characterization of ICAM-1 biophore to design cytoadherence blocking peptides

Journal of Molecular Graphics and Modelling, 2015
Peptides from natural sources are good starting material to design bioactive agents with desired therapeutic property. IB peptide derived from the ICAM-1 has been studied extensively as an agent to disrupt the non-specific binding of lymphocyte to the endothelial cells.
A, Mehra, Gaurav, Jerath, Vibin, Ramakrishnan, Vishal, Trivedi   +3 more
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Multiple Host Receptors for Malaria Cytoadherence Protein

Parasitology Today, 2000
Abstract Q. Chen et al. (2000) The semiconserved head structure of Plasmodium falciparum erythrocyte membrane protein 1 mediates binding to multiple independent host receptors. J. Exp. Med .
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Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence

Nature, 1985
Plasmodium falciparum infected erythrocytes containing mature trophozoites and schizonts sequester along venular endothelium and are not in the peripheral circulation of patients with malaria. Knobs appear on infected erythrocytes and are the points of attachment to endothelium.
D D, Roberts, J A, Sherwood, S L, Spitalnik, L J, Panton, R J, Howard, V M, Dixit, W A, Frazier, L H, Miller, V, Ginsburg   +8 more
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