Results 231 to 240 of about 48,300 (266)

Cytochalasin binding to macrophages

Cellular Immunology, 1978
Cytochalasin-sensitive structures are involved in macrophage motility, membrane recognition phenomena and the internalization of phagocytic particles. The purpose of this study was to characterize the binding of cytochalasins to rabbit alveolar macrophages.
Charles W. Parker, John P. Atkinson
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Cytochalasins: Structure-activity relationships

Phytochemistry, 1990
Abstract Seven cytochalasins, 17- O -acetylcytochalasin A and two derivatives of cytochalasin B were assayed for Pseudomonas syringae , Bacillus megaterium , and for Geotrichum candidum . Their ability to inhibit the growth of tomato seedlings and their toxicity to brine shrimp (% larvae mortality were also investigated.
Bottalico A, Capasso R, Evidente A, Randazzo G, Vurro M   +4 more
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Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes

Biochemistry, 1980
Twenty cytochalasins were tested for binding to and for inhibition of glucose transport in human erythrocyte membrane. In this membrane three cytochalasin B (CB) binding sites have been identified. All but three of the cytochalasins bind at site II. On the other hand, only nine of them, which are structurally closely related, bind at site I and inhibit
Amrit L. Rampal, Chan Y. Jung, Harold B. Pinkofsky   +2 more
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Effects of Cytochalasins on Lymphocytes: Some Distinctive Features of Cytochalasin-E

Journal of Immunopharmacology, 1984
Cytochalasin-E (CE) has specific properties that distinguishes it from other cytochalasin congeners. We have taken advantage of these in investigating the mechanisms operative in the effects of cytochalasins on lymphocyte proliferative responses to phytomitogens.
Chan Y. Jung, Basab K. Mookerjee
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Teratogenicity of cytochalasin D in the mouse

Teratology, 1977
AbstractCytochalasin D, a mold metabolite identified in food, was injected intraperitoneally in doses of 0.4 to 0.9 mg per kilogram on gestational days 7 through 11 and produced evidence of teratogenicity in two out of three strains of mice. Exencephaly, hypognathia and axial skeletal defects were found in strains C57BL/6J and BALB/c while no increase ...
Shepard, T H, Greenaway, J C
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Enhancement of viral infectivity by cytochalasin

Virology, 1973
Abstract Cytochalasins B and D enhance the infectivity of poliovirus; a 5-fold increase in viral titer occurs on treatment of cells with 4–6 μg/ml of either congener. At lower concentrations, however, CD is more effective than CB in increasing the infectibility of cells.
Stanley G. Sawicki, Gabriel C. Godman, Arline D. Deitch, Stuart W. Tanenbaum   +3 more
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The structures of cytochalasins A and B

Journal of the Chemical Society C: Organic, 1967
The structures of cytochalasins A and B, metabolites of Helminthosporium dematioideum showing novel effects on mammalian cells, have been determined. Cytochalasin B is identical with phomin. (–)-α-Methyladipic acid is shown to have the R-configuration contrary to a previous assignment; the absolute configurations of the Nupheus alkaloids therefore ...
R. N. Speake, J. J. Armstrong, W. B. Turner, D. C. Aldridge   +3 more
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Effects of Cytochalasins on Mammalian Cells

Nature, 1967
The cytochalasins—a group of mould metabolites—inhibit movement and cytoplasmic cleavage in cultured cells.
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The binding sites of cytochalasin D. II. Their relationship to hexose transport and to cytochalasin B

Journal of Cellular Physiology, 1977
AbstractCytochalasin B (CB) was able to compete with tritiated cytochalasin D (3H‐CD) for binding sites in HEp‐2 cells. The pattern of inhibition suggested that CB associates with a low affinity class of CD binding sites. Glucose and maltose did not inhibit binding of 3H‐CD to isolated HEp‐2 plasma membrane.
Janet Tannenbaum, Gabriel C. Godman, Stuart W. Tanenbaum   +2 more
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Actin assembly activity of cytochalasins and cytochalasin analogs assayed using fluorescence photobleaching recovery

Archives of Biochemistry and Biophysics, 1988
The effects on actin self-assembly of 9 common cytochalasins and 9 synthetic analogs have been assayed using fluorescence photobleaching recovery (FPR). The specific assembly activities of cytochalasins determined by this assay are (i) reduction of the fraction of actin molecules incorporated into filaments; (ii) increase of the steady-state diffusion ...
Grant A. Krafft, Bennie R. Ware, Elisse A. Walling   +2 more
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