Results 11 to 20 of about 46,080 (279)

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils [PDF]

open access: goldBMC Cell Biology, 2004
Background Cytochalasin B does not directly activate the oxygen-radical-producing NADPH oxidase activity of neutrophils but transfers desensitized G-protein coupled receptors (GPCR) into an active signaling state by uncoupling GCPR from the cytoskeleton.
Mellqvist Ulf-Henrik   +6 more
doaj   +2 more sources

Cytochalasin B modulates macrophage-mediated inflammatory responses. [PDF]

open access: yesBiomol Ther (Seoul), 2014
The actin cytoskeleton plays an important role in macrophage-mediated inflammatory responses by modulating the activation of Src and subsequently inducing nuclear factor (NF)-κB translocation. In spite of its critical functions, few papers have examined how the actin cytoskeleton can be regulated by the activation of toll-like receptor (TLR). Therefore,
Kim MY, Kim JH, Cho JY.
europepmc   +4 more sources

Effect of chemotherapeutic drugs and cytochalasin B on tunneling nanotubes in U87 MG cells [PDF]

open access: yesBMC Cancer
Intercellular communication in the tumor microenvironment has a major impact on therapeutic outcomes. In particular, highly aggressive cancers such as glioblastoma benefit from efficient cellular communication by developing resistance to therapy or by ...
Nicole Matejka   +2 more
doaj   +2 more sources

Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment [PDF]

open access: yesEuropean Journal of Histochemistry, 2014
The aim of the study was to assess the expression and subcellular localization of visfatin in HCT-116 colorectal carcinoma cells after cytokinesis failure using Cytochalasin B (CytB) and the mechanism of apoptosis of cells after CytB.
R.J. Bułdak   +8 more
doaj   +2 more sources

Towards the synthesis of cytochalasin B

open access: green, 1982
Chapter I of this thesis deals with the syntheses of the key fragments for use in a proposed synthesis of cytochalasins A, B and F. The chiral precursor 86 of the macrocyclic fragment of the target molecules was prepared in good overall yield from (+)-citronellol using a new reagent which was developed for this purpose.
S. Ramaswamy
openaire   +2 more sources

Cytochalasin B reacts with thiols [PDF]

open access: bronzeFEBS Letters, 1976
Lienhard, Gustav E.   +1 more
openaire   +4 more sources

NQO1-responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell-targeted Migrastatic

open access: goldSmall, EarlyView.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho   +7 more
openalex   +2 more sources

Testing Strategies of the In Vitro Micronucleus Assay for the Genotoxicity Assessment of Nanomaterials in BEAS-2B Cells

open access: yesNanomaterials, 2021
The evaluation of the frequency of micronuclei (MN) is a broadly utilised approach in in vitro toxicity testing. Nevertheless, the specific properties of nanomaterials (NMs) give rise to concerns regarding the optimal methodological variants of the MN ...
Tereza Cervena   +7 more
doaj   +1 more source

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